308. Dr. Will Cole: Insulin Resistance Is Fueling Your Cellular Aging

You might think eating clean is enough to stay young, but new research says otherwise. One in five people over 50 already have one organ aging faster than the rest of their body. Dr. Will Cole joins Gary Brecka to break down insulin resistance, blood sugar, cellular aging, mold and EMF toxicity, and SymphonyAge, the new DNA test that reveals exactly which organ is aging you fastest, from his book Heal Your Cells. Click here to join Gary’s VIP Community!: https://bit.ly/4ai0Xwg Get Dr. Will Cole’s book, “The Inflammation Spectrum”: https://amzn.to/4jnQe7r Listen to “ Dr. Will Cole “ on all your favorite platforms! YouTube:https://bit.ly/4jmEv9c Spotify: https://bit.ly/3Tu7Iaw Apple Podcasts: https://bit.ly/4xXaX8x Connect with Dr. Will Cole: Website:https://bit.ly/4iurxF0 YouTube: https://bit.ly/4jmEv9c Instagram:https://bit.ly/3GlSihK Facebook:https://bit.ly/4lGTEUh TikTok:https://bit.ly/4444EVw X.com: https://bit.ly/4cI59qw Thank you to our partners A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD AIRES: “ULTIMATE20” FOR 20% OFF: https://bit.ly/4a3Duze BAJA GOLD: “ULTIMATE10” FOR 10% OFF: https://bit.ly/3WSBqUa BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp CYMBIOTIKA: “BRECKACYM30” FOR 30% OFF: https://bit.ly/4tjyluP GENETIC METHYLATION TEST (UK ONLY): https://bit.ly/48QJJrk GENETIC TEST (USA ONLY): https://bit.ly/3Yg1Uk9 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S PEPTUAL: “TUH10” FOR 10% OFF: https://bit.ly/4mKxgcn SNOOZE: LET’S GET TO SLEEP!: https://bit.ly/4pt1T6V WHOOP: JOIN & GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW Watch the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 Intro of the Show 01:17 Dr. Will Cole on Cellular Health 04:45 How to Heal Leaky Gut Naturally 08:42 Intermittent Fasting for Gut Health 09:47 SIBO, H. Pylori & Fermented Foods 13:16 Heal Your Cells Book by Dr. Will Cole 16:55 Why Millennials Are Aging Faster 20:18 Epigenetics & Cellular Aging 26:59 Mitochondria & Best Longevity Blood Tests 30:10 Biological Age Test for Organs 33:00 Mold Toxicity & Histamine Intolerance 36:38 How to Manage Chronic Stress 39:08 Journaling for Stress & Trauma 43:02 Best Foods for Detox & Cell Repair 49:14 Therapeutic Plasma Exchange & Stem Cells 54:52 What It Means to Be an Ultimate Human Disclaimer: This podcast is for informational purposes only and does not provide medical advice. It is not intended for diagnosing or treating any health condition. Always consult a licensed healthcare professional before making health or wellness decisions. Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation. Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature. Learn more about your ad choices. Visit megaphone.fm/adchoices

• 0:00Speaker 00

  People born in the 90s, millennials, were aging more rapidly than people born in 1965. So there's people in their 20s, 30s, and 40s that have senior citizen cells and they don't even know it.

• 0:10Speaker 01

  I think it's high time that people recognize at scale the importance of cellular health, because very often we're just not getting down into microenvironment enough.

• 0:19Speaker 00

  We have this accelerated cellular aging, and the faster your cells are aging, you have an increased likelihood of a health problem of that specific organ. Living in our modern, broken world with environmental toxins, eating clean alone isn't going to cut it.

• 0:34Speaker 01

  If you're bathing your cells in a toxic soup and they've gone underdressed, and then you add the stress bucket to it, now you're at a breaking point.

• 0:41Speaker 00

  Because we know the things, what stress and rage and shame and trauma will do to you on a cellular level. You have to deal with the mental, emotional, spiritual just as much, if not more, than you deal with the physical. But the beautiful blessing, silver lining, and all of this is that when you know what you're dealing with, you can do something about it.

• 0:58Speaker 01

  For somebody that's compelled to take cellular health seriously, where's it start?

• 1:02Speaker 00

  It could all be boiled down to this.

• 1:17Speaker 01

  Hey, guys. Welcome back to the Ultimate Human Podcast. I'm your host, human biologist Gary Brecka, where we go down the road of everything, anti-aging, biohacking, longevity, and everything in between. And today's guest is actually someone I have a great amount of respect for in the industry, in the space, because he talks about a topic that goes lost, I think, even on a lot of functional medicine practitioners, and that is getting down to the health of your actual cells. And he's here today to not only talk about cellular health, but to talk about his new book that he co-authored with Dr. Josh Axe, another good friend of mine and mentor in the space. So, welcome to the podcast, Dr. Will Cole.

• 1:55Speaker 00

  Thanks for having me back, my friend. You made me a coffee today.

• 1:58Speaker 01

  Just a coffee, mold-free, certified organic.

• 2:03Speaker 00

  It's the best coffee I've had. What did you put in it? I mean, people are going to want to know what Gary Brecka made.

• 2:08Speaker 01

  I'll tell you what goes into this coffee. What goes in this coffee is certified mold-free organic coffee and then raw goat milk. So I foamed the raw goat milk and then about a tablespoon of raw maple syrup.

• 2:22Speaker 00

  Got it. Your side hustle could be barista. I mean, you could do it easily.

• 2:27Speaker 01

  You know, if it ever doesn't work out in the biohacking space, I could go into the barista. You know, I want to get into cellular health and I want to actually, because I think that you and I are aligned on so many different areas. You know, 12 years ago, when I started talking about mold, mycotoxins, viruses, parasites, heavy metals as a potential causes for immune disruption, chronic inflammation, immune activation. You know, I was laughed out of a lot of rooms.

• 2:55Speaker 01

  And it's becoming more accepted and more mainstream. You know, I love the adage that, the saying that, you know, when a fish gets sick, the first thing we do is clean the tank, right? Because it's so obvious, right? Fishes swimming around dirty water, murky water. And usually what we do is we clean up the terrain and the environment, and the fish gets healthy again. And by environment, I don't necessarily mean our external environment. I mean, this environment, the internal.

• 3:19Speaker 00

  The bio terrain.

• 3:20Speaker 01

  Yeah, the bio terrain. You've been a pioneer in talking about this. You and I, I think Dr. Pearl Mutter, were very early on the scene. I had Dr. Pearl Mutter here this week. He was a mentor of mine. In fact, in 2014, I read his book, Brain Brain.

• 3:35Speaker 00

  Brilliant, man.

• 3:36Speaker 01

  And then he wrote another one, Gut Brain Connection. Or one of those came first. It was Gut Brain Connection.

• 3:42Speaker 00

  Right. Yeah, he has Brain Maker, like a few different ones. And his new one, Brain Defenders, like Brain.

• 3:47Speaker 01

  Yeah, Brain Defenders, and he talks about Alzheimer's, dementia, and inflammatory conditions. But he gets to the root cause being gut, cellular health, and toxic exposure. And, you know, he talks very often about how your toxic bucket slowly fills up. And when it overflows, everything goes haywire. And it seems like something just happened to you, but it's been happening over a prolonged period of time. So, someone that's on this biohacking journey, which everyone that's watching this podcast is on this longevity, anti-aging, biohacking journey, whatever you want to call it, they're curious. But a lot of times they don't know where to start. And the gut is such a nebulous topic, right?

• 4:31Speaker 01

  You just take some probiotics and some colostrum, you're fine. How do you evaluate it? How do you assess it? And what do you do once you have that information? I would love to start there and then expand into the topics that you cover in the book.

• 4:45Speaker 00

  Yeah, improving gut health. Yeah, I mean, man, it's so important, right? Because it's the gatekeeper to everything. Something that we dive into, heal your cells, is this dysfunction of the cell. And even in functional medicine, we're looking at systems, right? We're looking at how the gut impacts the brain, or your hormones, or inflammation levels, your nervous system. But ultimately, it's a cellular dysfunction. And the cells that make up that organ, we want to understand what cell dysfunction is going on there. And the gut specifically, I mean, the gut lining is very, it's like one cell thin, and it's very thin. So it is very easy to become, those cells of the gut lining be more permeable. Things passing through the gut that shouldn't be able to pass through the gut,

• 5:27Speaker 00

  like undigested food proteins, like bacterial toxins that are high in lipopolysaccharides, these bacterial toxins. That's the seminal event that can cause systemic cellular inflammation, is when the gut is more permeable. So, here's what I'm finding, and certainly with your audience, I think it'll resonate with them. Because most of our telehealth patients know more than most people do. They're doing more than the average American. So, okay, they're beyond the basic stuff. And that, the old sort of cliched advice of just eat clean or eat real foods, isn't going to cut it, because there's a lot of foods that you, and I know this, that are not inherently bad. They're under the umbrella of real foods.

• 6:11Speaker 00

  But because of what we've done to the human microbiome, and of course, what we've done to our soil microbiome, and its intimate connection, and the larger human gastrointestinal system, there's a lot of quote-unquote "healthy" foods that aren't loving people's body back so far, so much. So, we have to figure out and meet someone's gut where it's at today, and then build resilience from there. So, these sort of hard and fast rules that apply to everybody, you have to go down and what, how can we create this proverbial cast? If someone has a broken bone, they have to put that cast on. How do we create a proverbial cast in someone's gastrointestinal system and microbiome to almost be, to gain resilience, to gain mending and healing? So, it could be soups and stews for some people, right?

• 6:56Speaker 00

  I mean, make something easy to digest. So, I think that's like a good, general, yeah, starting point for many people. Bone broth base. You can do a galangal, a ginger base if you want plant-based. You could do a seaweed broth, but predominantly bone broth base, with good puree, like soft cooked vegetables, puree them if you don't digest vegetables very well. Because these plant fibers and plant nutrients, plant anti-nutrients can be problematic for some people. But cooking them down almost like predigests the vegetables in some ways. And the meat is soft and it's cooked, it's broken up, so that's easy to digest as well. So, do some brothing and souping for, from a few weeks to a month.

• 7:41Speaker 00

  Now, there's caveats to that, because even bone broth can be high in histamine. So, if someone has histamine intolerance, that can make a good gut healing food like bone broth, not love some people back. There's so much bio-individuality for that. So, and then for that person, you'd have to do a low histamine protocol. But I would say, that's my point of saying, you can hear something that's good for the gut, for one person. Even if it's healthy, what works for one person may not be right for you. Which can be kind of maddening, but it, look at it a different way. Is that we're all unique, we're all at different stages of our healing. Let's find out what loves your body back. So, I think finding some stabilizing, nourishing meal, and then things that are calming, like calming teas, or something else that comes to mind,

• 8:25Speaker 00

  like ginger tea, peppermint tea, aloe juice, like whole leaf aloe juice, I find loves a lot of people's guts back. Those are some things to think about. And then intermittent fasting, like the sort of gut siesta is a good.

• 8:42Speaker 01

  I love that term, the gut siesta.

• 8:44Speaker 00

  Yeah, some sort of, yeah, gut siesta can be helpful, because that is a reprieve. Our gut has its own circadian rhythm. Certain bacteria are higher in the mornings, some are higher in the evenings, just like our hormones are. And then there's this communication between the gut and the hormones, right? So, fasting, even just not eating too late at night, just so you're fasting, at the very least, fasting through the night so you can rest your gut. That helps to reset and support microbiome balance. So, people have these bacterial overgrowths, these yeast and fungal overgrowths, and of course, inflammation and sort of a frenetic gut. That reprieve, that fasting period, whether you just are having a 12/12, and then you can progress from there.

• 9:26Speaker 00

  People can do 16, 18 OMADs for a time, cyclical OMADs. It's a great time to give the gut time, because digesting food requires a lot of energy, a lot of work. So, it could, healthy food can be stressing an already stressed-out gut. So, giving it just a break to allow your gut to work on repairing and not digesting is a good thing to consider.

• 9:47Speaker 01

  I think that's a great idea, too. And, you know, we've had a plethora of inquiries about SIBO and H. pylori, and actual infections, you know, in the stomach or in the gut lately, and how to address those without antibiotics. And if you, when you have a patient that has small intestinal bacterial overgrowth, and they can't do the standard fermented foods and things like that, that, I mean, I eat a ton of fermented foods.

• 10:16Speaker 00

  Yeah, me too.

• 10:17Speaker 01

  And I found that when I started to add sauerkraut, kimchi, and fermented foods and vegetables back to my regular routine. Now, I didn't have dysbiosis to begin with, but. My gut was the most regular it had ever been.

• 10:32Speaker 00

  Yeah.

• 10:32Speaker 01

  In terms of bowel movements, in terms of noise, in terms of, you know, bloating, gas, constipation, irritability, cramping, you know, I haven't had those in a very, very long time and they're a mainstay of my diet. But like you, I don't think that it is a catch-all, be-all, like everybody's just go get a can of sauerkraut.

• 10:52Speaker 00

  Yeah, start off low and slow. I mean, fermented foods are high in histamines too. So again, works great for some people, many people. I mean, I do great with it. You do great with it. But if it doesn't love your body back, check, it doesn't make that food bad. It just, you have to meet your gut where it's at. Start off low and slow because they are powerful modulators of the gut microbiome. So things like sauerkraut, kombucha, kombuchas, kebabs, yogurts, cheeses, that kind of stuff.

• 11:14Speaker 01

  Yeah. Listen, there's what I share on this podcast, and then there's what I share with my inner circle. If you've been following me for a while, you know how I hold nothing back here. But my VIP community, that's where the real magic happens. Picture this, you're struggling with energy crashes, brain fog, or just feeling like you're not operating at your peak, and you don't know where to get real answers. But here's what really sets this apart. You're not just getting my insights. When I have incredible guests on the podcast, VIP members get to submit questions for a private podcast segment. So that world renowned expert we just interviewed, you get exclusive access to their knowledge tailored to your specific situation. This section is under the private podcast section in the ultimate human community. And speaking of exclusive, you're getting my personal

• 11:58Speaker 01

  protocols, the exact tools I use for water fasting, gut optimization, and morning routines that have taken me decades to perfect. This isn't theory. This is what works in the real world. The community launches challenges throughout the year where you get direct access to me and my network of experts. It's like having a personal health advisory board for less than a hundred dollars a month. Your health is your wealth, and this investment pays dividends for life. Join the VIP community at theultimatehuman.com/vip and step into your ultimate potential. Now, let's get back to the ultimate human podcast. So let's pivot into Heal Your Cells, because I think it's high time that people recognize

• 12:40Speaker 01

  at scale the importance of cellular health, because very often, we're just not getting down into microenvironment enough. And we're not asking the question of what are we bathing ourselves in? You know, are they, are they just bathing in a toxic soup? In which case, you're not going to lever yourself out of that unless you really address, address things at a micro level. And so walk me through the book. I mean, what is Heal Your Cells about? What could, what could the reader expect to learn by, by parsing through that? It's a, it's a dense book. So.

• 13:16Speaker 00

  Yeah, it is a dense book.

• 13:17Speaker 01

  There's a lot of information.

• 13:18Speaker 00

  There's a lot of in there. But we wanted to make it beyond the basic stuff. People, we didn't want to, Dr. Axe and I didn't want to just write a book for the sake of it. I mean, we see patients full time, have podcasts, all that thing. So we really wanted to be meaningful. And it was born in part of something that him and I went through a few years ago. My dad, 63 years old, who, Dr. Pampa, we were at your house, actually, earlier this year. It was my, Dr. Pampa, if anyone knows him, he was my dad's best friend. I've known Dr. Pampa.

• 13:45Speaker 01

  He talked about that.

• 13:46Speaker 00

  Yeah, little kid. And he.

• 13:49Speaker 01

  He actually dissed on some childhood memories. I forget what it was, because I want to bring it to the podcast so bad right now. But like.

• 13:58Speaker 00

  He told some stories.

• 13:59Speaker 01

  Yeah, some good addition memories on you when you were like 10 years old.

• 14:02Speaker 00

  Yeah. Oh, my gosh. It was embarrassing. A whole room full of people. But anyway, so my dad was in the health space and on the outside, the picture of health. 63 years old, driving to pick my mom up from the airport, never made it. He lost consciousness, some cardiovascular event that made him pass out, and he went full, full speed off the road into a tree and died. And this is beyond the basics. He was already doing all that wellness stuff. So what's going on here? And it really, that same year, there was a study, and hindsight's 2020, we can't be god, we can't, we don't know everything. But in my mind, I'm a clinician, I see telehealth patients, I'm like, what was going on there?

• 14:45Speaker 00

  Like some things that I wish we would have done. But my dad was like a lot of people, both men and women. Men are the stereotypes here. But I see it with women, too. It's like, don't, I don't want to run the labs. I just know what to do. I know what to eat clean. I know exercise. So he did what he did in his 20s, 30s, 40s, and 50s. It just wasn't enough. So what, just, just enough, just what you do, the basic stuff, living in our modern, broken world with environmental toxins.

• 15:11Speaker 01

  Oh, yeah.

• 15:12Speaker 00

  Yet, eating clean alone isn't going to cut it. And that's just, I wish it was different, but it's just not different. Start with the basics. So of course, start there. But then test, and then you have to know what you have to lean into. Not everybody has to lean into dealing with forever chemicals and PFAs. But we know the science of these environmental toxins and how they can create inflammatory response of someone's arteries, creating heart attack and stroke. So for somebody that does eat clean, that does physical activity, and they have a health crisis, we have to look at these areas that are beyond the basics.

• 15:45Speaker 01

  Yeah.

• 15:45Speaker 00

  So Heal Your Cells, there was a study the same year that my dad died, it was published in Nature, it was out of Stanford. We talk about it in the book. But the researchers found one in five people over the age of 50, that equals about 22 million Americans, let alone all the people under 50 that I see on labs. So it's, the number's actually a lot higher, have one organ aging more rapidly than other organs, the sort of uneven aging. So this, their heart was aging faster, the brain was aging faster. And why this is important is the cells that make up that organ, if the brain was aging faster, the cells of the brain was aging faster, people in the study were at an 80% increased risk of some neurodegenerative problem.

• 16:27Speaker 01

  Wow.

• 16:28Speaker 00

  Alzheimer's, Parkinson's, like you were talking with Dr. Perlmutter. If your heart cells are aging more rapidly, you are at over a 200% increased risk of heart attack, stroke, heart failure, something like that. They looked at 11 different organs. And then just this past summer, just in June, they did a follow-up study that found even different types of cells within that same organ are aging unevenly.

• 16:49Speaker 01

  Wow.

• 16:49Speaker 00

  We're aging faster than ever. There's another study, roll, roll fast, and then I'll quit talking.

• 16:54Speaker 01

  Well, this is my jam.

• 16:55Speaker 00

  All right. 19. This was published in Nature, again, different group of researchers that found people, this is the UK Biobank, like looking at that data, and some data in the United States. People born after 1965 are aging more rapidly than people born prior to 1965 at the same age. And more shockingly, which, again, it makes sense when you see patients, but to see it in the journals was really shocking for me, is that people born in the 90s, millennials, were aging more rapidly than people born in 1965. So it's fair to say, people born in the 60s, 70s, 80s, 90s, millennials, Gen Z specifically, are every decade aging more rapidly than the decade prior. So there's people in their 20s, 30s,

• 17:39Speaker 00

  and 40s that have senior citizen cells, and they don't even know it.

• 17:43Speaker 01

  Wow.

• 17:43Speaker 00

  So that's why we wrote Heal Your Cells, is because, look, we have this accelerated cellular aging, and the faster your cells are aging, you have an increased likelihood of the, of a health problem of that specific organ. But the beautiful blessing, silver lining, and all of this, is that when you know what you're dealing with, you can do something about it. These are largely reversible, healable, overcomable, you can do something about it, but you have to know what you're dealing with, and not stick your head in the sand. So the middle ground is like, yeah, don't live in fear, because stressing about healthy things isn't good for your health. Don't become obsessive compulsive, or orthorexic, or some sort of stress ball around health. But then the other side is like, well, let's put our head in the sand, let's not even go there. Let's just, we're all going to die

• 18:27Speaker 00

  someday. That's sort of, many people say that. The middle ground is saying, let's do the best we can, be empowered, and then give the rest to God. We can't control everything, but we need to do something.

• 18:37Speaker 01

  Yeah. Yeah. And when you talk about do something, so somebody that's compelled to, you know, again, they're, they're watching this podcast, they're doing all the right things, just like you said, they're eating a whole food diet, mobility's non-negotiable, they're somewhat focused on their sleep. They have decent relationships, you know, familial relationships, friendships, what have you, which I think is a really healthy ecosystem. We don't talk that much about community and connection at the level, at least that I think we should. In fact, I think it was the Harvard study, that longitudinal study that said that the quality of your relationships is one of the biggest determinants, if not the single biggest determinant of your longevity. And that isolation is extraordinarily

• 19:21Speaker 01

  detrimental to human survival. And we know this because of broken heart syndrome, right? Everybody's had a grandparent or great-grandparent that passed away after being married for 40, 50, 60 years, and you see the consequences. But, you know, for somebody that's compelled to. Take cellular health seriously. What are the stages that they go through? I would say that probably the vast majority of my listeners have already done some lab work. They're taking some supplements. They have some rationale behind that. They've likely done some other kind of testing, genetic testing or what have you. But what do these deep dives on cellular health look like? Do they look at toxicity? Do they look at cellular function? How do you measure it?

• 20:06Speaker 01

  You talk so much about the importance of the mitochondria.

• 20:10Speaker 00

  Yeah.

• 20:11Speaker 01

  I feel like you're the mitochondrial pioneer.

• 20:13Speaker 00

  Thank you.

• 20:14Speaker 01

  Yeah. Which I agree with.

• 20:16Speaker 00

  Yeah.

• 20:17Speaker 01

  Where's this start?

• 20:18Speaker 00

  Yeah. So, I mean, in the book, we dig into these hallmarks of aging and every year, every few years, right, there's lumping in new ones. But we have to understand what's going on with the cell. If you want, if you're saying, okay, look, if I have brain fog, fatigue, if I have some inflammatory problem, if I'm dealing with something and I am doing all the things, if you're better off than you were, you know, if you're better off because you are doing the things, okay, great. But if you know I'm stuck at this plateau, I'm not where I want to be, I'm speaking to you. Is that, why are you dealing with that? There's still cellular confusion. I mean, if you look at Sinclair's work, right? At Harvard, right?

• 20:56Speaker 01

  Harvard.

• 20:57Speaker 00

  Yeah, Harvard, yeah. The information model or theory of aging and chronic disease, like the understanding that our cells are confused, that our genetics haven't changed, the genes inside your nucleus of your cell, they haven't changed in thousands and thousands of years. But what has changed dramatically in such a finite period of time, and you're putting that in context with the totality of human history, it's what researchers call a genetic, epigenetic mismatch. This chasm between our cells and the world around us. Our cells are living in a brave new world. And this mismatch is why our cells are confused. That's how the researchers define it, is that there's this proverbial scratching happening in the cell. It's kind of a scratched CD or scratched record, where if you put the record to CD

• 21:39Speaker 00

  on, it will play, but it's going to be jumping around. The message is there, but it's not going to be clear. That's what happens. The code that that cell needs is, it's hard to-

• 21:50Speaker 01

  You're dating yourself, by the way, by using a record as an example.

• 21:53Speaker 00

  I know, it's like, you can't really say it, right?

• 21:55Speaker 01

  10% of our audience is like, well, record was, I've never heard of this.

• 21:58Speaker 00

  But you can't even say anything, because like analog is like dead, but I mean, let's bring it back.

• 22:03Speaker 01

  Let's bring it back.

• 22:04Speaker 00

  Let's bring back analog.

• 22:05Speaker 01

  I remember records, man, I'm not-

• 22:06Speaker 00

  But you know what I'm talking about. Something physical, something, the software, right, is damaged, but the hardware is there in pristine. So, there's a cellular communication issue where the cell, when the cell loses recognition of self, and that could be molecular mimicry with autoimmunity, when the cell is behaving kind of disorganized, it's what the researchers call ex-differentiation, is that the brain cell forgets to be a brain cell, the heart cell forgets to be a heart cell, the ovarian cell forgets to be an ovarian cell, and that's where chronic health problems reside. So, what do we need to do to reprogram our cell, or to, the researchers talk about methyl adaptogens, like what are ways to regulate methylation, to sort of buff and clean that scratched CD or record?

• 22:51Speaker 00

  And there's lots of ways to do that, but you have to find out what are the pain points for your specific case, what's creating cellular confusion for you. So, as I say, the big areas are going to be the foods that we're eating, and it's granular, depending on what loves your body back. Not just what you eat, but when you eat, and you look at the research of people talking about a lot of chronic health problems, you get being chronobiological in nature, meaning we're, back to the fasting piece, we're always eating foods that don't love us back, and we're not giving us our body a break from that. So, that cellular siesta, that fasting that we talked about earlier, we need that, because that helps to shift your cells to more of a healing state. It's our relationship to light, the dirty light, and that's throwing off our cellular

• 23:36Speaker 00

  clocks. And there, our cells have lost track of time, because we're in front of our blue light with our phones all day long, and it's throwing off that sleep-wake cycle. And then, the other things, real quick, and we can dive into any one of these, but I would say environmental toxins, obviously, herbicides, pesticides, microplastics, forever chemicals, heavy metals. And then I would put biotoxins on there like mold. But I would like to get your take on this, is I think the mold conversation is at least exacerbated because of EMFs. Because mold has always been toxic. I mean, the Bible talks about mold, Leviticus says to burn the house down.

• 24:12Speaker 01

  Right.

• 24:13Speaker 00

  But thank the Lord, we have remediators now, we don't have to do that. But I do think that mold spores are so, myotoxins are so more irritated from constant electricity, man-made EMFs that we are exposed to, where it's making a bad problem worse.

• 24:27Speaker 01

  Yes.

• 24:28Speaker 00

  And then I would say this, like you said, it's stress and trauma, it's some sort of mental, emotional, spiritual thing. Chronic stress, unresolved trauma, spiritual disconnection from God, and with other humans. That in a nutshell, so to answer the question is, what are the areas that I just said that are creating dysregulation for your cells? For some people, it's going to be more food. For some people, when you run labs, it's more environmental toxins. For some people, it's their relationships, or unresolved trauma in their life, or their relationship with God, spiritual disconnection. For a lot of us, it's going to be the entourage effect of a lot of different things.

• 25:04Speaker 01

  Right.

• 25:05Speaker 00

  That it's like, yeah, you don't have to have it all figured out, but you need to start having a hard conversation with yourself of what's causing cellular dysregulation in your body.

• 25:13Speaker 01

  Yeah. And I love that you actually point out, everything that you're talking about is the environment, the terrain within us. And, you know, stress comes from our outside environment, but you see people that have extraordinarily level, extraordinary levels of stress from the outside looking in, they're calm as a cucumber. I mean, they're just managing and handling it. Some of the, you know, most prominent type A, burn the candle at both ends, entrepreneur-minded clients that I've had, have been some of the most centered and calm. If you look at their life from the outside, it seems very chaotic.

• 25:54Speaker 01

  And it seems overtly demanding, but they have a handle on it, and inflammatory markers are low, cellular health is in good shape, they're also doing all the things, and they manage it. Other people, you know, stress becomes a breaking point. And I love that you also pointed out how multifactorial it is, you know, if you're, if you're bathing your cells in a toxic soup, and it's all of these environmental toxins, and they've gone unaddressed, and then you add the stress bucket to it, you know, now you're at a breaking point. And, and it's hard to say, and I know people, when they watch a podcast, want you to give them the one thing, that they, it's this, and if you fix this, everything gets better.

• 26:36Speaker 00

  Yeah.

• 26:37Speaker 01

  But truth is, you know, it's, it's too multifactorial when you talk about human beings. And I think it's probably why this book is going to end up being such an appropriate, the timing of the book's going to be so appropriate, because how first would we evaluate cellular health? Like, what do you, when you say a cell is healthy, what do you mean?

• 26:59Speaker 00

  Yeah. You mentioned mitochondria. I mean, that is, it would be hard to find someone not impacted by mitochondrial dysfunction that's struggling with some sort of chronic health problem, or even just suboptimal health. Like, there's going to be a component to why they feel the way that they do is going to be mitochondrial dysfunction. But, I mean, the mitochondria are, I mean, just the genesis of it, the idea that mitochondria have their own DNA, it's wild to me.

• 27:24Speaker 01

  Yeah.

• 27:25Speaker 00

  Right? I mean, that, I mean, depending on how you look at it from more of a secular or a spiritual standpoint, or both, really, it should be one and the same, is that the idea that at creation, at the dawn of time, that these sort of bacteria, these soil-based organisms were engulfed in human cells, and now they're living in every cell of our body, communicating to our microbiome, mitochondria are descendants of ancient bacteria. We're from the dust of the earth, the Bible says. So, whether you believe in God or not, I mean, there's something to be said through the creation process, that we have bacteria in every cell of our body, and it's, they're stressed out. So, as people can have leaky gut syndrome, which we talked about, and then people can have increased blood-brain barrier permeability, what does that mean? That means the gut cells are more permeable, or the blood-brain barrier cells are more

• 28:10Speaker 00

  permeable. But ultimately, what's really happening? All those systems and organs are made up of cells, the cells are actually leaky, the mitochondria are leaky, they're, they're, they're supposed to create ATP or cellular energy, but they're starting to leak these reactive oxygen species. They're these pro-inflammatory cells. So, it's like the hermetic phrase, as above, so below, as within, so without. Our cells are defensive, our cells feel, really, all the things that I just mentioned of what's stressing our cells out, our cells feel unsafe. Because when, really, it could all be boiled down to this, when mankind pretends to be God, there's unintended consequences, and sometimes intended consequences. And that's what we're paying for the price, that's why there's human discord in our life,

• 28:55Speaker 00

  and that's why there's physiological climate change, if you will, in the form of chronic inflammation and cellular confusion. So, I mean, how you figure out, to answer your question more pointedly, specific biomarkers you would want to run? You could look at clinical biomarkers, I would say, the average, easy-to-get labs that could show how quickly or how slowly your cells are aging from a global standpoint, it's looking at insulin resistance. Because we know that's gasoline on cellular aging.

• 29:26Speaker 01

  Oh, yeah.

• 29:27Speaker 00

  I mean, upwards of 93% of the United States is insulin resistant, that is a gasoline on cellular aging fire. So, to look at your glucose, fasting blood sugar, we want it under 90 in functional medicine, your A1C under 5.5, triglycerides under 100, that's your circulating fat, HDL or good cholesterol, we want it above 59, and those inflammation markers, high sensitivity C-reactive protein, HSCRp, we want under 1, homocysteine, we want under 7. And then, if you have access to it, still a conventional lab, running a nuclear magnetic resonance, like looking at the small-dense LDL particles. Understanding your metabolic health is important.

• 30:07Speaker 00

  Is that understanding every cellular, the uneven aging that Stanford was looking at? No. There's a test called Symphony Age, it's from True Diagnostics, we run it for telehealth patients. It was in partnership with Yale. So it's not apples to apples. Stanford was looking at these specific proteins, which I think they're working on a direct to consumer lab.

• 30:26Speaker 01

  Like glycan age, like the

• 30:27Speaker 00

  Yeah, probably similar to, I don't know what, yeah, it's a certain protein. So they're able to look at specific tissues of that organ, the Stanford study that I talked about early. So they're working on that, but as close to apples to apples as you can get, it's this DNA methylation test from True Diagnosis called Symphony Age, which I have no connection to them, but they just are something that we utilize clinically. They look at 11 organs, just like Stanford looked at 11 organs, looking at DNA methylation. They looked at, they looked at over 100 different, 100,000 different DNA methylation sites and correspond that to clinical biomarkers and morbidity case studies. So, and to understand where the different organs are aging. So we do have access to that

• 31:11Speaker 00

  now is what I'm trying to say. It's a blood spot test. So I would look at the blood spot DNA methylation and you can look and see, okay, maybe you're, this person's heart is aging faster. This next person, their brain is aging faster. And you can give specific thing therapeutics, recommendations, foods to focus on, whatever it is, to be a little bit more organ specific to that person, because the cells of that organ are aging more rapidly. And that's where I think like getting precision, getting precise on the rapidity of someone's organ aging faster will be more effective. Cause maybe like globally, globally, they're pretty much fine, but that organ's a problem for them. And that, I think someone like my dad could have benefited from being more organ specific and beyond sort of the general advice.

• 31:55Speaker 01

  So I've been working out with my son lately, trying to keep up with him and his high rocks competitive athletes. And I've been starting to use this perfect amino pre-workout. I really like it. It's got BH4, it improves nitric oxide output, but it actually seems to stay after the workout and not crash. There's no stimulants. So no caffeine, no Ma Long, nothing that gives you that kind of amped feeling. You just feel like you're maybe better able to move during the workout. Like you have better blood flow. So if you're in the market for a pre-workout, check out the perfect amino pre-workout. It's my favorite now. Now let's get back to the ultimate human podcast. So you get this methylated gene test and you get this basic panel with some of the

• 32:33Speaker 01

  classic inflammatory markers, HSCR, insulin resistance. When you get that data back, then what do you do? Talk about maybe some journeys that you've walked on with some patients that came in with what you found what and treated it how?

• 32:51Speaker 00

  Yeah.

• 32:51Speaker 01

  Cause I think really landing this for the audience is, is important. Number one extends hope. And number two, someone is going to identify with the story you're about to tell.

• 33:00Speaker 00

  Yeah, there's so many people come to mind. We talk a lot about case, we talk about a lot of case studies in heal your cells because I agree with you. Like hearing other people's story helps you to know that you're not alone.

• 33:14Speaker 01

  Yeah.

• 33:14Speaker 00

  And it helps to metabolize your own stress to know that you're not alone. Like we were talking about community before we started recording, that even just reading about other people's story to know how to get to the other side of what seems impossible is profoundly, it sparks hope. It sparks like, I'm not alone. I'm not crazy. I knew, I knew what was going on. Cause you start to doubt your intuition whenever you're gaslit in a system that doesn't listen to you. So I hear you. There was one person that comes to mind, her name's Lindsay. We talk about her in the book and she's still a telehealth patient with me now. I just saw her on a group call last week. She's doing amazing. But when she met me, man, she was bedridden.

• 33:55Speaker 00

  This is someone that was on TV, in the public space, doing different things in that world of sort of anchoring shows and hosting things like that. And she could eat five foods. She, I might say five foods, it was a handful. I don't know the exact number, but it was under 10 foods, where every food just didn't love her body back.

• 34:17Speaker 01

  Just histamine.

• 34:18Speaker 00

  Yeah. Histamine response, exactly. Histamine response. She was reacting to everything. Fod maps, histamines, oxalates, all of it. And it wasn't the food's fault. It was stressing and already stressed out. She had no resilience. The food was stressing out and already stressed out immune system. So we ran, and she'd seen lots of doctors, lots of conventional doctors, a lot of people in the functional medicine space. It wasn't a lack of brilliance at addition from the doctors. I mean, they all know all the best studies out there, but it was putting all the pieces together, acting sort of like a clinical quarterback for her to see, okay, what is, what were the missing pieces there? So she had, it was mold. It was EMF sensitivity

• 35:01Speaker 00

  that was exacerbating the mold. So yeah, we're always going to be exposed to EMFs guys. So don't, unless you're going to go off the grid and live in Montana in a yurt somewhere. But it's about building resilience, living in a modern world, doing the best you can. Doesn't have to be perfect, but we started emptying that proverbial bucket. Your bucket is, I'm to even use the cell analogy, some people, if your cells are a bucket, some people have a capacity to handle more than others. That's your methylation gene variance, your HLA, your detoxification gene variance. The more single and double gene variance you have, these SNPs, that's going to shrink that proverbial cellular bucket. You can't change the bucket size, but

• 35:43Speaker 00

  you can change what you put in it. So that's going to be the mold, the stress, the stress and trauma was a massive piece for her too. And it's still something she's working on. Actually just was telling me last week. So it's dealing with the physiological and the mental, emotional, spiritual, all those things that I talked about earlier that kind of caused cellular, the cells to be unsafe. What makes the cells feel unsafe? So the things that were causing her cells to feel unsafe was the mold piece that over EMF exposure that was exacerbating the mold toxins. It was, the mold was releasing more mycotoxins because the mold was irritated by the EMFs. And then it causes her cells to be more permeable to receive more of the mold

• 36:22Speaker 00

  toxins. And I would say building gut resilience is of course part of that, but how can you do that when your nervous system feels completely fight or flight all the time? So nervous system regulation was a massive piece, dealing with the stress and trauma.

• 36:38Speaker 01

  And I want to come back and peel that back because I, I think you're hitting on a really, really strong point. And I don't want to interrupt your

• 36:44Speaker 00

  No, no, interrupt only one.

• 36:46Speaker 01

  But when we talk about stress management, and I think that's sort of such a great catchall term, but, but people are like, yeah, but how do I manage stress? First of all, what do you want me to get rid of my spouse, get rid of my kids and quit my job? Because that's where my stress comes from. It's my kids, my spouse and my job. And so living in a modern world, we have to become, in some cases, we have no choice but to adapt. And what are some of the practices, like practical practices people could use to adapt? I know what I do, but.

• 37:14Speaker 00

  Well, I would say to, the author Eckhart Tolle, I think, gives a lot of helpful, practical advice here. He talks about what's your relationship with the present moment? Are you using, are you making friends with the present moment? Do you see it as a means to an end? Or do you see it as an enemy? Because when you're talking about current, current chronic stress and then unresolved past trauma is another thing. But if we're just talking about current stress, what's your relationship with life itself? What's your relationship with the present moment?

• 37:42Speaker 01

  Wow, that's a really good one.

• 37:44Speaker 00

  And

• 37:45Speaker 01

  Framing.

• 37:46Speaker 00

  And boil it every situation that's stressing you out a bit. And I tell telehealth patients this all the time. Can you, can you, maybe it's this stressful thing at work, right? Or maybe it's a relationship. Can you change it, leave it, or accept it? Pick one of those three things. Because if you're not picking one of those three things, you're creating dysregulation for yourself, cellular unsafety for yourself and everyone around you. Cause a frenetic stress, dysregulated person is going to impact, it's going to sabotage your relationships. So change, leave or accept it. So maybe it's a stressful thing at your work. Maybe can you quit your job? I see some telehealth patients quit their job because it's really toxic for them. But maybe they can. That's unpractical for a lot of people. Maybe they can change it. Maybe they

• 38:30Speaker 00

  could go and speak up for themselves and advocate for themselves and have the tough conversations, job or relationship, right? Or maybe it's accept. Maybe you can't change or leave it. So that's the analogy that you said, like for your kids, right? You can't, hopefully you're not going to leave your kids, right? But can you find what the Bible calls the pieces, the peace that passes all understanding? Can you do radical acceptance? It's called radical for a reason. Cause it's this deep spiritual work of saying, you know what, God, I can't change or leave it right now, but can you give me peace despite my circumstances right now? They need to have that come to Jesus moment for themselves in any situation that's causing them stress. That's deep work.

• 39:08Speaker 01

  Leave it or accept it.

• 39:09Speaker 00

  Pick one of the three.

• 39:10Speaker 01

  Yeah.

• 39:10Speaker 00

  And journaling is another thing that I have people, every telehealth patient do. 20 minutes a day. It's called journal speak. It is metabolizing stored stress and trauma in the body. Cause that stress and trauma, you're in a resistance to the present moment or the, what's happening from the past that's living in your body. It's creating a lot of cellular unsafety. So putting pen to paper, pencil to paper and writing out 20 minutes a day, a good prompt can be, what does it feel like to be me today? Which is kind of a heavy question for someone that doesn't feel good or is stressed out in their life.

• 39:41Speaker 01

  Right.

• 39:42Speaker 00

  Writing things you never would say to anybody out loud and purging that from your body. It's like a, a sort of a somatic detox that can happen when you release that. Cause we know the things that what stress and rage and shame and trauma will do to you on a cellular level. It will make your cell, it's the cell defense response, it's cell danger response. Your cells cannot differentiate a physiological threat and the mental, emotional, spiritual threat.

• 40:10Speaker 01

  I agree.

• 40:11Speaker 00

  What can you do to make your cells feel safe? And for some people, it's their relationship with light, with the present moment. For some people, it's their things that in their past they have to deal with, but you have to deal with the mental, emotional, spiritual, just as much, if not more than you deal with the physical. Because even when you talk about food, like how many people are in self sabotage with food because of the mental, emotional, spiritual? They can't even stick to a protocol or some sort of way of eating because of these past programming they have from their stress or trauma.

• 40:40Speaker 01

  I love that. You know, journaling is a way to, there's an old business book called Put the Moose on the Table. And I use it all the time in my company. And it's basically take the biggest problem, put it under the brightest light. And they give a lot of historical context around this, but how the best relationships, the best companies, the best governments.

• 41:01Speaker 01

  Were all, one of the central themes was they took the hardest thing and they put it under the brightest light. And, and sometimes I think people have a lot of shame around reaching out, but, but journaling can be very interpersonal. You don't have to share it with your spouse. You don't have to share it with your family. But it can be a way for you to, as you say, metabolize that, that, that stress. But if you pretend like there's no mousse on the table, then, um, you know, it just, it just sort of eats you from the inside.

• 41:31Speaker 00

  It totally does. And it's, yeah, it creates a cascade of dysfunction on the inside and the outside.

• 41:36Speaker 01

  Yeah. And, you know, I've found in clients of mine that, you know, when we frame sleep, you know, I remind them, sleep's not about being tired. It's about your body feeling safe to shut off. When you look at broad categories of disease, you know, there's what, 82% of all autoimmune disease found in women. That doesn't mean autoimmune disease is selected by sex, selected by weakness. And what makes them weak is like internalizing a lot of emotion. And, and, and then that becomes like the termites that just nibble away at cellular health. I want to get back down to the cell too, because what are, you know, so first you, you, you're framing the mental, emotional, spiritual impact on cellular

• 42:20Speaker 01

  health. Let's move over to toxicity, because I think now finally, we are starting to accept and mainstream allopathic medicine that, yeah, maybe metals, mold, mycotoxins, parasites, viruses, glyphosate.

• 42:37Speaker 00

  Forever chemicals.

• 42:38Speaker 01

  Forever chemicals can, can create these events that don't show up on normal labs, right? We always talk about the patient is fine on the, on the lab, but is a disaster sitting in your office.

• 42:53Speaker 00

  Yeah.

• 42:53Speaker 01

  And so, you know, someone that wants to go on that detox journey, where does that framing start?

• 43:02Speaker 00

  Yeah. I would say it can start with, it starts with food.

• 43:06Speaker 01

  Okay.

• 43:07Speaker 00

  And targeted ways to support. Something that we talk about in the book that's in all of this research in the scientific literature, looking at cellular rejuvenation, right, for lack of better words, is xenohormesis is one thing that comes to mind. Like, we know hormetic effects are one way to make, to, to, to buff that scratch C D A record. So your cell can recognize what it's supposed to do. So it is like a cell boot camp, a cell, cellular somatic baptism, if you will, is different ways to do it. So fasting's one way to do it. It's a hormetic effect. Ketogenic diet, fasting mimicking, actually fasting or fasting mimicking diet, like the ketogenic diet. It's, it's lowering these

• 43:50Speaker 00

  pro-growth pathways like mTOR to increasing things like autophagy, which is cellular recycling, increasing mitophagy, mitochondrial autophagy. Your cell, your body knows what to do. You just need to give it the chance to do so. So you need to lower pathways like mTOR, which is needed to build muscle, but you don't want to always be high. Your cell thinks, okay, I'm in pro-growth mode, but we need to be in repair mode more than ever before.

• 44:16Speaker 01

  Yeah.

• 44:17Speaker 00

  And finding that balance of growth, but also repair. But the specific food that comes to mind of focusing on are these xenohormetic compounds, which is just like fasting or cold punching or sauna, or all of these different ways.

• 44:30Speaker 01

  Red light.

• 44:31Speaker 00

  Red light. They're all xenoh, they're all hormetic, but xenohormesis comes from plant compounds that have gone through stressful things in their life. So think of it as like, um, plants that went through hard times where it's like, maybe it's the soil was drought. It was the heat of the sun. It was bugs biting it. Think of the deep colored, rich pigments in things like berries and the pomegranates, or the bitterness of extra virgin olive oil, or the bitterness of rosemary, thyme, basil, herb, or the bright colored aspects of turmeric. The bitterness and the bright colors, focusing on those things, as long as they love your digestion back to tolerance, teach our cells, like the stress

• 45:13Speaker 00

  that the, the life that that plant went through, the cells of that plant teach our cells to be stronger, to be more resilient, to repair. A lot of these compounds are senolytics, like they break down these senescent pro-zombie cells that are pro-inflammatory. These zombie cells will, just like if you're dysregulated, if our cells dysregulated, it creates dysregulation in the whole organ that's there. So those plant compounds that I talked about there, whether it be extra virgin olive oil, like a bitter tea, oolong pu'er tea, green tea, herbs and spices, berries, pomegranates, the bitterness, the bright colors are a way to help with cellular repair mechanisms. I think it's a profound, profound tool, because

• 45:58Speaker 00

  it helps with cell repair.

• 45:59Speaker 01

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• 46:41Speaker 01

  you. Head to joinwhoop.com/ultimate. That's join W H O O P dot com/ultimate to get started. Now let's get back to the Ultimate Human Podcast. And then when you find yourself in the presence of some of these, let's say that you've done one of the classic tests for toxicity, like environment wellness, or total toxicity test, or any number of tests. And, and you find the presence of these metals, metals and molds, I think, big ones. Then how do we start to incorporate specific detox into our lives? Because, you know, like we said, these people are the ones that have already, that are

• 47:23Speaker 01

  doing all the things. I love that, the practice of journaling. I love the framing of either, accept it, get rid of it, or what was it?

• 47:35Speaker 00

  Change, leave, and accept.

• 47:36Speaker 01

  Change, leave, and accept, you know?

• 47:37Speaker 00

  Yeah, sorry, I forgot to answer your question about detoxing.

• 47:40Speaker 01

  Yeah, I want to get into that.

• 47:41Speaker 00

  Yeah. So the food is first, but then supplements like glutathione, obviously, like these tripept, tripeptide of glutathione. But the bitterness, that's where I lost my train of thought, sorry, is that the bitterness, like things like sulforaphane, like broccoli sprouts, these are, these flavonoids, these polyphenols, these anthocyanins, these sulfur, sulfur compounds, all of these foods that I just mentioned, help with cellular detox. So that's combination of it helps to up-regulate these cellular repair mechanisms and detox. And then from there, the supplements can be glutathione. I love activated charcoal, zeolite, diatomaceous earth, these binders that can be good. And what else? Like sweating is another one, like just.

• 48:22Speaker 01

  Huge.

• 48:23Speaker 00

  Sweat. And if you don't have access to a sauna, like do an Epsom salt bath, you know, get, do a hot yoga, and just work out, get in, get in the sun. I mean, even your relationship with light and like actually God made light, not our fake dirty light that humans make.

• 48:41Speaker 01

  Right.

• 48:41Speaker 00

  But like getting outside, getting your feet in, in the earth, that change, actually the electrical frequency of the earth shifts our own cellular electrical system to allow our cells to feel safe. So it can do what the, what it was supposed, what it was created to do, which is to protect you and to clear these environmental toxins.

• 49:01Speaker 01

  Yeah.

• 49:01Speaker 00

  And then the light there, it helps to reset that cell clock. But also if you're sweating, then you've kind of got multiple benefits from some healthy amounts of sunlight. And then from there, you can get nitty gritty, like, I think you just did therapeutic plasma.

• 49:14Speaker 01

  Yeah, in use for recess.

• 49:16Speaker 00

  Yeah, okay. Yeah. So something like.

• 49:17Speaker 01

  But I'm on T P E too.

• 49:18Speaker 00

  Yeah. Therapeutic plasma exchange has an amazing place for someone that done all the things I just said. I think T P E and things like T P E can be a wonderful tool to, okay, you've done all the core stuff, but these numbers aren't moving where I want it to be. These glyphosate levels or whatever environmental toxins you're talking about. And I think that's where these more advanced therapeutics can be helpful.

• 49:42Speaker 01

  I'm actually really excited for, you know, T P E you can do here in the U S. In use for recess, not yet, but it's coming. And I know there's a lot of states that are expanding right to try, for example. I want to say it's Montana and. Montana and New Jersey, or New Hampshire, that have already expanded their state right to try, meaning if you have a debilitating, I mean, if you have a terminal or debilitating illness, you know, it used to be just terminal when the medical system had given up on you and you were terminally ill. But what if the medical system's given up on you and you're just chronically ill? And so I'm excited about the horizon that I see there.

• 50:27Speaker 00

  Same with stem cells. You mentioned like state rights, like we have it, you have it here in Florida, right?

• 50:32Speaker 01

  Florida's a great state.

• 50:33Speaker 00

  Yeah, but the mechanism, how those work is that they, we talk about mitochondria. One of the mechanisms is that they're these tunneling microtubules. The stem cell therapy, the stem cells actually donate their own mitochondria for, to your cells to say, you've got this, let's, I'll give you my own mitochondria so you can actually heal and repair itself. So I think stem cells and the sort of cellular communication that they can improve to, again, allow your cell to recognize what it was meant to do all along and reprogram, if you will. I think these emerging therapies, really, the way that they work in part, if not exclusively, is because they're improving cellular communication so the cell can actually function the way God created it.

• 51:16Speaker 01

  Yeah, you know, cells communicate, stem cells communicate by these things, secretomes, and, or what we call exosomes. And we can even isolate those and use those to provide additional growth factors. And I'm like, oh, you're on a gas, and I can tell you that in tissue and wound repair specifically, as well as other areas, neurocognitive decline, I've seen with my own eyes, you know, some of the, some of the benefits of these. And I'm also encouraged by that. For, just to back up for a second, the people that don't know what therapeutic plasma exchange is, can you just give us a broad description of it?

• 51:50Speaker 00

  So it's taking a certain portion of blood and get put, and there's different ways, I think, different clinics and different protocols do it differently, but are replacing your plasma with a synthesized albumin. Is that how most of them do it?

• 52:05Speaker 01

  Like a sterile albumin.

• 52:06Speaker 00

  Yeah. So it's a way to, to do a deep cleaning in the blood, which is ultimately the cells.

• 52:12Speaker 01

  Right.

• 52:13Speaker 00

  For somebody that's, I've seen, okay, we can get mold toxins or environmental toxins down 80%, and then without it, and then that's filling in the gap for these areas where the body's just not letting go, it's holding it on. So it's a way to do some deep cellular cleansing.

• 52:27Speaker 01

  Yeah. I noticed when I did it, I had, I did the first treatment, and then I puffed up like a pufferfish. So did my wife.

• 52:36Speaker 00

  Interesting.

• 52:37Speaker 01

  Like puffy eyes. My joints felt very stiff, my hands were swollen. I was talking to the physician at the clinic, and he said, that's perfectly normal. If you reduce the concentration in the blood plasma, you're going to have migration from the tissues. So your body's behaving exactly as it should. And now I just got my last toxic swimmer back, and it was all in the grain.

• 53:02Speaker 00

  Wild.

• 53:03Speaker 01

  For the first time. And I'm one of those people's doing all the things, right?

• 53:07Speaker 00

  Yeah.

• 53:08Speaker 01

  It was like, you know, some of those words I couldn't even pronounce. I'm like, what the hell is jet fuel in my blood?

• 53:13Speaker 00

  Yeah, where's the jet fuel coming from?

• 53:15Speaker 01

  Jet fuel, where's the, where's the accelerant from a raid can, you know?

• 53:19Speaker 00

  That's what I'm talking about. These sort of gnarly things that are like, okay, where's this person even getting it? He's not a pilot. Where's the jet fuel coming? But that's how broken and messed up our world is. It's like, you have to do a deep cellular cleansing sometime. Now, you don't have to start there. It's like you've never done something healthy. Don't go to say like, okay, let's do TPE. But it's there for people who need it and want it. And yeah, I want these things to become more accessible for people, because I think it'll save lives.

• 53:44Speaker 01

  Yeah.

• 53:45Speaker 00

  When you look at the mechanism of action of why someone can do all the things and die from a heart attack or stroke, or get cancer, or have an autoimmune condition, it's these type of things that are just a product of, again, mankind's brokenness.

• 53:58Speaker 01

  Well, Dr. Cole, Heal Your Cells, I think, right place, right time. And I think, instead of being ahead of its time, it's at the right time, because I think the, the world is ready and longing for a book like this. I think that we have sufficiently woken up, post-pandemic, whatever you want to credit for doing this, on a global scale, and the level of curiosity out there right now, and the thirst for information. So I appreciate the timing of this book. And I know you and Dr. Axe both put your heart and soul into it. I'll put a link to the book in my show notes. I want to take you into my VIP community, because they're, they have

• 54:38Speaker 01

  a lot of questions for you. And, but before we, before we go in there, I wind down all my podcasts by asking my guests the same question. What does it mean to you to be an ultimate human?

• 54:49Speaker 00

  Yeah. Let me think of how I would answer this. I would say, look, we talk a lot about in the book today, we talked a lot about today, about adding life, adding years to your life. And I love the latest longevity science as much as anybody else, right? This is what we do. I have a passion for it. But a lot, we can lose the plot sometimes, and just this, it becomes a sort of fear-based thing of the fear of death, or the promise for the future. But, okay, I don't want to operate like that. How can we add life to your years in the here and now? And I see so many people, they've so, in our space,

• 55:34Speaker 00

  the sort of the biohacker space, I think you and I have talked about this before offline, is that they are so kind of looking for the future and not enjoying their life now. You know, it's, it's like, oh, we're just, we're doing this protocol and that protocol, and we're just like, it's all consuming, all the health stuff. I think the ultimate human is remembering your place in this, and remember the human part of that. And like, what's your relationships like? What's your relationship with God like? How are you, like, are you enjoying your life? Like, why are you doing all this wellness stuff? It should be to be someone that has the fruits of the spirit in your life, love, joy, peace, patience,

• 56:14Speaker 00

  kindness, goodness, self-control. Like, that's the, the product, that's the, the manifestation of someone that I think is why that you should be doing the wellness stuff, all the wellness stuff. I guess another way of saying it is just remembering your why, and letting your why be something noble.

• 56:32Speaker 01

  Yeah. Love that, man. That is a great explanation. Guys, I will put a link to the book in the show notes. If my audience wants to find out more about you, where can they find you?

• 56:43Speaker 00

  Thanks, man. Everything's at DrWillCole.com, D R W I L L C O L E. The links to Heal Your Cells, the telehealth podcast, which you've been on, the art of being well. And let me just say, before we wrap up, like, thank you so, so, so much for just being like the same, the person that everybody sees. You're like this in real life.

• 57:02Speaker 01

  Thank you.

• 57:03Speaker 00

  You're just, you are a blessing to so many people, whether the world sees it or not. And most of the time, they actually don't see it. And not everybody's like that. Some people, there's like an on-camera version of them, and then there's, they're different. You are who you are, which is a blessing to people. And that is, that is the ultimate human, actually. And you, you practice what you preach truly, in the unseen. And I just wanted to say that publicly.

• 57:26Speaker 01

  That really means a lot to me. I really do appreciate that, and especially coming from someone like you. That means, that means quite a bit to me. And until next time, guys, that's just science.