The Generalist

AI Got Good at Language. Now It’s Learning the Language of Life. (Eric Nguyen, Co-Founder and CEO of Radical Numerics)

Aug 4, 2026

The Token Budget Problem Nobody Is Talking About (Matan Grinberg, Co-Founder & CEO of Factory)

Jun 30, 2026

Own or Be Owned: Why Every Company Needs Its Own AI Model (Yash Patil, Co-Founder & CEO of Applied Compute)

Jun 23, 2026

What America Is Missing Between Sanctions and Nuclear War (Bryon Hargis, Co-Founder & CEO of Castelion)

Jun 2, 2026

“Our Goal Is to Build an Electrical Engineer.” (Davide Asnaghi, Co-Founder & CEO of Diode)

May 19, 2026

Investing Like A Mystic: How Cyan Banister Finds Outliers (Co-Founder of Long Journey Ventures)

May 5, 2026

The Future Of Drug Discovery Is 4 Billion Years Old (Viswa Colluru, Founder & CEO at Enveda)

Apr 21, 2026

How a 20-Person Startup Won Gold at the Math Olympiad—Tying With OpenAI & DeepMind (Tudor Achim, CEO of Harmonic)

Apr 14, 2026

30% Of Network Engineers Are Retiring. What Happens Next? (Anil Varanasi, Co-Founder & CEO of Meter)

Apr 7, 2026

Why One Superintelligence Is More Dangerous Than a Thousand (Vincent Weisser, CEO & Co-Founder of Prime Intellect)

Mar 24, 2026

Why Robots Still Struggle With Simple Tasks (And What Might Finally Change That) | Karol Hausman, Co-Founder & CEO of Physical Intelligence

Mar 17, 2026

America’s Electric Power Grid Is Broken. This Startup Is Trying to Fix It. (Zach Dell, co-founder & CEO of Base)

Mar 10, 2026

Everyone Is Betting on Bigger LLMs. She's Betting They're Fundamentally Wrong. (Eve Bodnia, Founder & CEO of Logical Intelligence)

Feb 24, 2026

How Bolt Survived An 85% Revenue Crash And Became Europe's Ride-Hailing Champion (Markus Villig, Founder & CEO)

Feb 19, 2026

The Private Company Bringing Nuclear Enrichment Back to America (Scott Nolan, CEO of General Matter)

Feb 3, 2026

Programming Sunlight: How Reflect Orbital Is Building Satellites to Redirect Light From Space (Ben Nowack, Founder & CEO)

Jan 20, 2026

Nothing’s Carl Pei on Building a $1B Smartphone Company, Why He Left OnePlus After 10 Days of Retirement, and Why He Thinks About Death Every Week

Jan 13, 2026

Why Being a Generalist VC Is a Competitive Advantage (Aydin Senkut, Founder & Managing Partner at Felicis Ventures)

Dec 9, 2025

Joey Krug on Prediction Markets, Crypto Treasuries & the Next Era of On-Chain Finance (Partner at Founders Fund)

Dec 2, 2025

How a Solo Founder is Reshaping Global Finance (Parth Garg, CEO of Aspora)

Nov 18, 2025

How Do You Build a New Singapore? Inside Próspera’s Bet on Private Governance (Erick Brimen, Founder & CEO)

Nov 11, 2025

Why Psychedelics Might Be the Breakthrough That PTSD Patients Need (Kevin Ryan, The Godfather of NYC Tech)

Oct 28, 2025

The Trillion-Dollar AI Hardware Opportunity (Navin Chaddha, Managing Partner at Mayfield)

Oct 21, 2025

Biological Time Travel: How Cryopreservation Could Transform Medicine (Laura Deming, CEO & co-founder of Until)

Oct 14, 2025

"This feels like 1996": Why a16z's Martin Casado believes the AI boom still has years to run (General Partner)

Oct 7, 2025

How to be Agentic in the Age of AI (Cate Hall, CEO of Astera)

Sep 30, 2025

Can Humans Stay Smart in the Age of AI? (David Krakauer, President of the Santa Fe Institute)

Sep 23, 2025

Building Beautiful Homes with Robots: The Future of Construction (Salar al Khafaji, CEO & Founder of Monumental)

Sep 16, 2025

What Makes Something Alive? Assembly Theory and the Origins of Life (Sara Walker, Theoretical Physicist)

Sep 9, 2025

Reviving Forgotten Technologies: How Airships, Supersonic Flight, and Geothermal Energy Could Transform Our World (Eli Dourado, Head of Strategic Investments at Astera Institute)

Aug 19, 2025

Inside General Catalyst’s $1B+ Bet on Fixing Healthcare (Hemant Taneja, CEO & Managing Partner)

Aug 12, 2025

The Future of Crypto: Stablecoins, AI Integration, and the Path to Mass Adoption (Jesse Walden, Founder & Managing Partner at Variant)

Aug 5, 2025

AI Agents Are Here: What They Can Already Do—and What’s Next (Stanislas Polu & Harrison Chase)

Jul 29, 2025

The Decade of Data (Tomasz Tunguz)

Jul 22, 2025

Why the Real Computer Revolution Never Happened (Alan Kay & Anjan Katta)

Jul 15, 2025

No Rivals

Jul 8, 2025

Existential Risk and the Future of Humanity: Lessons from AI, Pandemics, and Nuclear Threats (Toby Ord, Author of "The Precipice")

Jun 24, 2025

Are We Alone In The Universe? Sara Seager on Exoplanets, Venus, and the Hunt for Alien Life (Astrophysicist and Planetary Scientist at MIT)

Jun 17, 2025

Antimemetics: Why Some Ideas Resist Spreading (Nadia Asparouhova, Writer & Researcher)

Jun 10, 2025

Creating Stars in a Bottle: The Race to Commercialize Fusion Energy (Vinod Khosla & Bob Mumgaard)

Jun 3, 2025

The Semiconductor Century with Chris Miller (Author of “Chip War”)

May 27, 2025

How Anduril Is Reimagining the Defense Industry: Faster Tech, Ethical AI, and a New Kind of Deterrence (Trae Stephens, Co-Founder & Executive Chairman of Anduril)

May 20, 2025

Inside Substack’s $650M Playbook for the Future of Media (Chris Best & Hamish McKenzie, Co-Founders)

May 6, 2025

Lessons from 20 Years of Venture Capital (Roelof Botha, Managing Partner & Steward at Sequoia Capital)

Apr 29, 2025