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215. Dr. Mindy Pelz: Why Fasting Stops Working for Women—Menopause, Stress & Hormones

Extend Podcast with Darshan Shah, MD

Hosted by Dr. Darshan Shah

35m
Transcript

Original podcast

Summary

Written by a model from the transcript; not yet reviewed.

This episode features Dr. Darshan Shah and Dr. Mindy Pelz discussing menopause, evolutionary biology, and how stress impacts fasting and metabolic health for women. Dr. Pelz explains that menopause is not a decline but a neurological remodeling that prepares women for leadership by shedding people-pleasing tendencies. They examine why traditional fasting advice often stops working for women trapped in chronic stress or fight-or-flight nervous system states, introducing a framework based on green, yellow, and red nervous system zones. Listeners will gain actionable insights on how to customize fasting, food choices, and self-care practices according to their biological stress state.

  • Track your hemoglobin A1C during menopause to monitor metabolic flexibility and reduce the risk of dementia. 9:44
  • Adjust your fasting window to 13 to 15 hours and avoid extreme fasts when your nervous system is stressed. 17:59
  • Take regular nervous system quizzes to determine whether your body is in a green, yellow, or red zone. 15:24
  • Incorporate infrared saunas and slow daily activities to stimulate the parasympathetic nervous system and lower cortisol. 19:14

Chapters

  1. 0:03
    Podcast Introduction and Host Greeting

    Dr. Darshan Shah opens the episode, introduces the podcast and sets the stage for the interview with Dr. Mindy Pelz.

  2. 0:49
    Book Overview: Age Like a Girl

    Dr. Pelz explains the personal significance of her new book and its focus on menopause.

  3. 2:05
    Why Menopause Extends Human Life

    Dr. Pelz discusses evolutionary reasons why humans live long after reproductive years.

  4. 3:00
    Brain Remodeling During Menopause

    Exploration of how estrogen decline reshapes the brain, affecting behavior and leadership traits.

  5. 6:05
    Hormone Replacement and Brain Changes

    Dr. Pelz explains that HRT does not fully reverse menopause‑related brain remodeling.

  6. 9:17
    Practical Advice for Women in Menopause

    She offers actionable steps: self‑knowledge, monitoring A1C, and communicating needs to loved ones.

  7. 12:29
    Fasting for Women: Timing and Sensitivity

    Dr. Pelz outlines how menstrual cycle phases influence safe fasting practices.

  8. 14:00
    Closing Remarks and Resources

    Final thoughts, upcoming projects, and where listeners can find Dr. Pelz’s work and community.

  9. 15:00
    Using the Nervous System Quiz

    Introduction to an interactive quiz that tailors fasting and nutrition plans to individual stress states.

  10. 21:37
    Nervous System States: Green, Yellow, Red

    Explanation of the three states and how they affect fasting, diet, and exercise choices.

  11. 25:23
    Reset Academy Community Program

    Dr. Pelz describes her membership group that supports women through fasting, nutrition, and community.

  12. 29:46
    Purpose and Identity After Menopause

    Discussion on redefining life goals and using tools like conversation cards to foster self‑reinvention.

Highlights

  • 1:15

    Menopause as Evolutionary Leadership Preparationinsight

    Dr. Mindy Pelz explains that estrogen decline during menopause causes brain remodeling that eliminates people-pleasing neurons, preparing women for leadership and protector roles.

  • 5:49

    Hormone Replacement and Brain Remodelinginsight

    Even with hormone replacement therapy, women maintain lower estrogen levels than in their twenties, allowing the natural evolutionary brain remodeling project to still occur.

  • 15:32

    Nervous System States and Fastingstrategy

    Green represents balance for fasting, while yellow indicates sympathetic fight-or-flight where fasting and intense workouts can actually cause weight gain and insulin resistance.

  • 21:37

    Nourishing the Red Nervous System Statestrategy

    When the nervous system shuts down into a red conservation state, heavy fasting and workouts should be replaced with bone broth, steamed foods, and gentle walking.

  • 24:24

    Reset Academy Experiment Resultsdata

    In an experiment with 300 women who adjusted their diet and fasting to their nervous system state, 90 percent successfully transitioned from red to yellow and yellow to green.

Quotes

  • “menopause wasn't the end of something, it was the beginning of something.”
    Dr. Darshan Shah · 1:47
  • “the neurons in your brain that kept you addicted to people pleasing go away.”
    Unnamed speaker · 3:04
  • “hemoglobin A1C. Know your blood sugar. Know if you're metabolically flexible.”
    Unnamed speaker · 9:55
  • “If you're in a state of chronic stress, fasting, you might need to do less fasts.”
    Unnamed speaker · 13:38
  • Timeline 20:44–21:59

About this episode

What if menopause isn't the beginning of your decline—but the beginning of your most powerful chapter? And what if the reason fasting isn't working for you has more to do with stress than willpower? In this episode, I welcome back Dr. Mindy Pelz, bestselling author of Fast Like a Girl and Age Like a Girl, to explore how menopause, hormones, and nervous system health influence the way women age. Dr. Pelz challenges the traditional narrative around menopause, explaining how declining estrogen may affect the brain, behavior, and identity. We also discuss why intermittent fasting isn't one-size-fits-all, how chronic stress can affect metabolism and weight management, and why sometimes doing less is exactly what your body needs. In this episode, you'll learn: How menopause and declining estrogen can influence brain health, mood, and behavior Why fasting strategies may need to change throughout a woman's menstrual cycle and menopause How chronic stress, cortisol, and nervous system regulation relate to metabolic health Why fasting harder and exercising more aren't always the best solutions for weight gain How sleep, breathwork, nutrition, and recovery can support your nervous system Why menopause can be an opportunity to rediscover your purpose and identity The biggest takeaway? More isn't always better. Understanding what your body needs—and adjusting your approach as you age—may be one of the most powerful ways to support your long-term health. Learn more about Dr. Darshan Shah: Website: drshah.com https://drshah.com Clinic: next-health.com https://www.next-health.com/ Instagram: @DarshanShahMD and @extend_podcast Learn more about Dr. Mindy Pelz: Nervous System Questionnaire: NervousSystemQuestionnaire https://bit.ly/NervousSystemQuestionnaire Age Like a Girl Book: bit.ly/alagbook https://bit.ly/alagbook Fast Like a Girl Book: bit.ly/fastlikeagirlbook https://bit.ly/fastlikeagirlbook Resetter Collaborative Facebook Group: bit.ly/resettercollaborative https://bit.ly/resettercollaborative Reset Academy: bit.ly/resetacademymembership https://bit.ly/resetacademymembership Fast Like a Girl Certification Course: bit.ly/flagwaitlist https://bit.ly/flagwaitlist Thank You to Our Sponsors! IM8: Try IM8 with a 30 day money back guarantee! Use code DRSHAH at checkout at im8health.com/drshah https://im8health.com/drshah for 10% off! Timeline: Timeline, powered by Mitopure, just dropped in price! Check it out using link shop.timeline.com/DRDARSHANSHAH https://shop.timeline.com/DRDARSHANSHAH for 20% off when you subscribe!

Transcript

0:00
35:13

6,362 words · 2 speakers

Speaker names marked are inferred from speaking time and the show’s known hosts — they are not voice-verified.

Topics

  • Fast Like a Girl
  • Finnish sauna
  • Age Like a Girl
  • Reset Academy
  • Mayo Clinic
  • Santa Cruz
  • Infrared sauna

Page updated · transcript and summary are machine-generated