
Written by a model from the transcript; not yet reviewed.
In this episode, the hosts unpack a wild week in tech, biotech, and business news, starting with Moderna's stock plummeting after leaked Phase 3 cancer vaccine trial results failed to match lofty investor expectations of a 49% reduction in risk. They also examine a bizarre twist where a fitness and gambling influencer named Togi flipped his position from calls to puts right before the crash, fueled by prophetic dreams and AI prompts. The conversation moves on to Madison Square Garden's controversial cybersecurity test, which used fake emails promising employees custom championship rings to catch phishing vulnerabilities, and a sprawling 147-acre Alaska property listed for 12.5 million dollars.
Additional discussions cover Joe Lonsdale's appearance on CNBC from a private jet where he jokingly recommended Grok for parenting advice, and archival footage of Palmer Luckey and Ben Lamb discussing military bioengineering applications like genetically engineered dire wolves. The hosts mix in banter about upcoming video game releases, countdowns to Christmas, and various internet memes, delivering a fast-paced look at modern tech culture and media narratives.
Hosts introduce the show, discuss Call of Duty gameplay, and set the episode tone.
The hosts explain Moderna’s leaked trial data, the stock’s wild ride, and investor expectations.
They detail influencer Togi’s dream‑based trades, his timing of Moderna’s crash, and the resulting losses and gains.
They describe the 147‑acre Alaska property, its features, and the seller’s background.
The episode covers the Knicks’ fake ring email, the phishing test, and the broader cybersecurity implications.
Hosts discuss the hack, patient data exposure, and potential motives behind the cyberattack.
The conversation explores bio‑engineering of dogs for military use and speculative future applications.
Hosts conclude the show, recap highlights, and remind listeners of the Christmas countdown.
Moderna Cancer Vaccine Data Leakdata
Moderna stock plunged after preliminary Phase 3 cancer vaccine data leaked early, showing a 42% risk reduction rather than the anticipated 49%.
Phase Three Trial Results Disappointdata
The much-anticipated Phase 3 trial of over 1,000 patients showed a 42% reduction in relative risk, falling short of investor hype.
Influencer Trades on Dreamsstory
Fitness and gambling influencer Togi timed a massive short position on Moderna after dreaming that the stock crashed.
Joe Lonsdale CNBC Plane Hitinsight
Joe Lonsdale called into CNBC from a private aircraft without a virtual background and discussed using Grok for parenting advice.
MSG Phishing Test Using Ringsstory
Madison Square Garden sent a phishing test email promising employees championship rings, forcing those who clicked into cybersecurity training.
A 147-acre property in Palmer, Alaska featuring mountain views and a private helipad was listed for 12.5 million dollars.
Genetically Engineered Military Animalsinsight
Archival footage featured Palmer Luckey and Ben Lamb discussing potential military applications for genetically enhanced animals like dire wolves.
“Data from Moderna's cancer therapy leaked, and the stock has been on this wild ride up and down, fueled by speculation that they cured cancer.”
“The early results that they had sort of gestured towards in the Phase 2 was a 49% reduction in relative risk of cancer recurrence or death compared to KEYTRUDA alone.”
Diet TBPN delivers the best of today’s TBPN episode in 30 minutes. TBPN is a live tech talk show hosted by John Coogan and Jordi Hays, streaming weekdays 11–2 PT on X and YouTube, with each episode posted to podcast platforms right after. Described by The New York Times as “Silicon Valley’s newest obsession,” the show has recently featured Mark Zuckerberg, Sam Altman, Mark Cuban, and Satya Nadella. TBPN is made possible by: Ramp - https://ramp.com Public - https://public.com Cisco - https://www.cisco.com Console - https://www.console.com CrowdStrike - https://www.crowdstrike.com Figma - https://www.figma.com MongoDB - https://www.mongodb.com NYSE - https://www.nyse.com Railway - https://railway.com Shopify - https://www.shopify.com/ Follow TBPN: https://TBPN.com https://x.com/tbpn https://open.spotify.com/show/2L6WMqY3GUPCGBD0dX6p00?si=674252d53acf4231 https://podcasts.apple.com/us/podcast/technology-brothers/id1772360235 https://www.youtube.com/@TBPNLive
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