
Hosted by John Coogan and Jordi Hays
Written by a model from the transcript; not yet reviewed.
This episode of TBPN covers a wide range of developments across technology, artificial intelligence, media mergers, and infrastructure. The hosts discuss IBM experiencing the biggest share drop in its 115-year history following a server business reset, Demis Hassabis calling for a US-led standards body to test frontier AI models, New York Governor Kathy Hochul placing a one-year pause on new AI data centers, and the ongoing legal battle led by California Attorney General Rob Bonta against the Paramount and Warner Brothers Discovery merger. Later, several guests join the show to discuss their companies, fundraising rounds, and industry insights, including TerraFirma on construction robotics, Greylock on their new $1.5 billion venture fund, Reflection on frontier open models and a compute deal with Nebius, Chai Discovery on computer-aided design for molecules, State Affairs on policy tracking, and Cypher Digital on AI data center development in West Texas.
Hosts open the show, discuss IBM’s recent stock decline and its AI strategy.
Breakdown of IBM’s software, consulting, and infrastructure businesses and their margins.
Hosts segue into Demis Hassabis’s call for a US-led AI standards body.
Discussion on how AI can enhance filmmaking without replacing human creativity.
Exploration of emerging vertical drama apps and their market impact.
Debate over Hollywood’s role versus independent AI app developers.
Analysis of potential IP conflicts and regulatory cooperation between the US and China.
Light‑hearted segment about industry gatherings in Sun Valley and their cultural significance.
Interview with TerraFirma’s founders about building a robotics‑powered construction company.
Discussion on how regulatory approvals affect the speed of robotic construction projects.
Overview of Greylock’s 18th fund, focus areas, and capital allocation philosophy.
Interview with Reflection’s co‑founder on building frontier open models and securing compute.
Panel discussion on balancing innovation with regulatory oversight in the AI era.
Deep dive into Chai Discovery’s AI‑driven chemistry tools and their pharma focus.
The conversation explores how AI has moved from hype to practical deployment in major pharma companies, accelerating drug discovery and changing industry dynamics.
The hosts discuss the recent $400 million raise, detailing the high-profile investors and the significance of the valuation for the AI drug discovery platform.
Guests explain how State Affairs builds a knowledge graph of federal and state policy changes, using journalism and AI to provide real-time insights for businesses.
IBM Stock Dropsdata
IBM experienced the biggest share drop in its 115-year history as the stock fell 25% following a narrative reset around its server and mainframe business.
Demis Hassabis Proposes AI Bodyinsight
Google DeepMind CEO Demis Hassabis called for a US-led standards body to test new frontier-class AI models for national security threats and cyber, biological, and nuclear risks.
New York Data Center Moratoriumstory
New York Governor Kathy Hochul placed a one-year pause on new AI data centers in the state to conduct environmental impact assessments on energy demand and water use.
Paramount WBD Merger Legal Challengedebate
California Attorney General Rob Bonta filed a lawsuit to block the $111 billion merger between Paramount and Warner Brothers Discovery, citing archaic standards in theatrical and cable distribution.
TerraFirma Robotic Constructionstrategy
TerraFirma retrofits existing Caterpillar and John Deere machines with custom robotic software to operate as a full-stack construction company and automate heavy labor.
Greylock Raises $1.5 Billiondata
Greylock Partners announced its 18th venture fund totaling one and a half billion dollars, focusing on early-stage founders and new AI infrastructure and applications.
Reflection Signs Nebius Compute Dealdata
Reflection signed a billion-dollar deal with Nebius to secure the massive compute required to train frontier open models and ensure open intelligence remains accessible.
Chai Discovery Raises $400 Milliondata
Chai Discovery raised a $400 million round at a $3.8 billion valuation led by Index, Kleiner Perkins, Sequoia, and Dimension to build a design suite for molecules.
“IBM is absolutely nuking. The stock is down 25%.”
“Since the launch of chat GPT, IBM has done, uh, really, really well.”
“In 2019, IBM acquired Red Hat for 34 billion and spun off its traditional managed infrastructure outsourcing business, in 2021.”
“The US is well positioned, given its economic and technical standing, to take the first step in developing such a framework.”
“$111 billion deal, bring Warner Brothers Discovery into the fold with Paramount.”
“AI creates extraordinary opportunities in every aspect of, of business, industry, commerce, everything else.”
“We take existing Caterpillar machines and we retrofit them.”
“We could operate at 168 hours a week. We could be at 100% utilization rate and we're not.”
“I created some really, you know, interesting situations where, you know, we would go into, a pharma company and we'd be presenting some data.”
“We raised 400 million dollars at a 3.8 billion dollar valuation. We're super lucky to be partnered with Index, Kleiner, Parkin, Sequoia, and Dimension, who are the sort of the largest checks in, in the rounds.”
(00:21) - IBM Nukes (07:36) - Demis Govt Plan (20:08) - NY Pauses AI Datacenters (25:38) - Can Pretty Data centers Win? (27:58) - Clanker Whales (29:23) - Dylan Byers, a founding partner and senior correspondent at Puck, is known for his in-depth coverage of the media industry. He discusses the challenges David Ellison faces in merging Warner Brothers Discovery with Paramount, highlighting opposition from Democratic state attorneys general, particularly California's Rob Bonta, who seeks to block the deal on grounds that Byers argues are outdated given the current media landscape. Byers also touches on the potential for Hollywood studios to relocate operations in response to regulatory pressures, emphasizing the evolving nature of the entertainment industry. (59:54) - Noah Schochet, co-founder and CEO of TerraFirma, discusses how he and his co-founder, both former SpaceX engineers, founded the company to revolutionize the construction industry by integrating robotics and automation to accelerate building processes. They retrofit existing heavy machinery with custom-built software and hardware, enabling remote operation and increased efficiency. Schochet emphasizes that while full autonomy may not be cost-effective due to construction's numerous edge cases, achieving approximately 75% autonomy with human oversight can significantly enhance productivity. (01:10:58) - Saam Motamedi, a partner at Greylock Partners, focuses on early-stage investments in AI, cybersecurity, and enterprise software. He discusses Greylock's new $1.5 billion fund, Greylock 18, aimed at supporting early-stage founders, particularly in AI. Motamedi emphasizes the vast opportunities in AI across the technology stack, from foundational models to applications, and highlights the potential for multiple significant winners in emerging categories due to the transformative impact of AI on various industries. (01:21:48) - Ioannis Antonoglou, co-founder, president, and CTO of Reflection AI, previously served as a founding engineer at DeepMind, contributing to projects like AlphaGo and AlphaZero. In the conversation, he discusses Reflection AI's mission to develop frontier open models, emphasizing the need for exceptional talent and substantial computational resources, exemplified by their recent billion-dollar deal with Nubius. He also reflects on the rapid advancements in AI over the past 15 years, highlighting the importance of adaptability and the exponential nature of progress in the field. (01:31:25) - Jack Dent, co-founder and president of Chai Discovery, discusses the company's development of an AI-driven platform for molecular design, likening it to a "Computer Aided design suite for molecules" that enables the creation of new medicines. He highlights the platform's focus on the pharmaceutical industry, emphasizing its potential to revolutionize drug discovery by designing molecules that can effectively target diseases. Dent also notes the rapid advancements in AI models for drug discovery, citing a significant improvement in success rates from 0.1% to 16% over the course of 2025. (01:44:50) - Evan Burns & Jamie Seltzer. Evan Burns, CEO and co-founder of State Affairs, discusses the company's mission to provide real-time insights into policy and regulatory changes affecting businesses, aiming to shift companies from reactive to proactive engagement in the legislative process. He highlights the challenges of navigating antiquated state government systems and the importance of having on-the-ground journalists to gather timely information. Burns also mentions their recent $70 million funding round led by Coatue and Founders Fund, emphasizing plans to expand coverage to city and international levels. Jamie Seltzer is the co-founder of State Affairs, an AI-powered policy intelligence platform that combines original statehouse reporting with AI to help governments, businesses, and advocacy organizations track and understand legislation across all 50 states. He is also a general partner at LightShed Ventures, investing in technology, media, and communications companies. (01:56:57) - Tyler Page, CEO of Cipher Digital, discusses the company's transformation from bitcoin mining to developing AI data centers, highlighting their current projects totaling 700 megawatts across three sites in West Texas. He emphasizes the importance of site selection, community engagement, and addressing concerns such as water usage and noise, noting that Cipher strives to be a good neighbor by contributing to local infrastructure and ensuring minimal environmental impact. Page also outlines the company's capital market strategy, detailing their approach to financing and partnerships with hyperscalers like AWS and Google. TBPN is made possible by: Ramp - https://ramp.com Public - https://public.com Cisco - https://www.cisco.com Console - https://www.console.com CrowdStrike - https://www.crowdstrike.com Figma - https://www.figma.com MongoDB - https://www.mongodb.com NYSE - https://www.nyse.com Railway - https://railway.com Shopify - https://www.shopify.com Codex - http://openAI.com/codex Follow TBPN: https://TBPN.com https://x.com/tbpn https://open.spotify.com/show/2L6WMqY3GUPCGBD0dX6p00?si=674252d53acf4231 https://podcasts.apple.com/us/podcast/tbpn/id1772360235 https://www.youtube.com/@TBPNLive
26,536 words · 11 speakers
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