
Written by a model from the transcript; not yet reviewed.
This episode explores the landscape of open models and physical AI with Mingyu Liu, Vice President of Cosmos Lab at NVIDIA. The conversation covers why open models are critical for innovation and commercial freedom compared to relying solely on APIs, how physical AI applies artificial intelligence to physical devices like robots, autonomous vehicles, and automated factories, and what differentiates neural simulation from classical physics-based simulation. The discussion also examines NVIDIA's Cosmos world models, which fuse world understanding and world simulation to help developers train smarter physical AI systems and coordinate multi-agent workflows.
The guest and hosts examine the practical technical differences between large language models and physical AI architectures, noting that physical devices operate under real-time constraints, power limitations, and batch-size-one inference demands. They discuss how world models serve as virtual testing environments to accelerate policy iteration for self-driving cars and robotic arms without relying strictly on physical fleet testing. Finally, the episode highlights how NVIDIA provides open weights, training frameworks, and recipes on platforms like GitHub and Hugging Face to empower developers and researchers to build customized solutions.
Hosts Daniel and Chris introduce the Practical AI Podcast and set the stage for the episode.
Mingyu Liu, VP of Cosmos Lab at NVIDIA, joins to discuss NVIDIA’s focus on open models and their importance.
Mingyu explains how open models drive innovation in academia and enable commercial flexibility for NVIDIA customers.
The conversation shifts to physical AI, covering automotive, robotics, and other verticals, and how open models support these domains.
Mingyu delves into world models, simulation, and their role in building policies for autonomous systems.
Hosts wrap up, promote the Midwest AI Summit, and thank NVIDIA for its contributions to open AI.
Discussion on how multiple AI agents interact in manufacturing, logistics, and other scenarios, highlighting coordination challenges.
Mingyu outlines technical and organizational hurdles, emphasizing the need for an open, collaborative ecosystem.
Mingyu provides practical guidance on accessing NVIDIA’s open models, training frameworks, and community resources.
Why Open Models Drive Innovationinsight
The guest explains that open models allow researchers and developers to inspect code, understand underlying concepts, and innovate in ways that closed APIs do not permit.
Commercial Innovation And Freedominsight
The guest argues that commercial companies need open models for innovation and freedom to build custom applications beyond what frontier foundation model providers foresee.
Defining Physical AI Applicationsinsight
Physical AI is defined as artificial intelligence deployed in physical devices that perturb the state of the world, spanning automotive, factory automation, and robotics.
Fusing Understanding And Simulationinsight
The latest Cosmos model fuses world understanding and world simulation into an omni model that supports text, action, audio, and video inputs and outputs.
Neural Versus Classical Simulationinsight
The guest contrasts classical rule-based physics simulators with neural data-driven simulation, where models approximate physical outcomes by recognizing visual patterns.
World Models For Policy Testingstrategy
World models enable developers to verify policy checkpoints in simulation before deploying them to real cars or robots, significantly speeding up the iteration loop.
Multi-Agent Manufacturing Futureinsight
The guest envisions a future of specialized multi-agent systems where LLM planners, mobile platforms, robotic arms, and self-driving trucks collaborate on factory floors.
“Open models are a key piece of what is important in the AI ecosystem.”
“You can leverage API to solve the problem. But with the open model, you can do more than what's available in API.”
“The representation allow you to do simulation, what it can do for physical AI.”
“Open model is not just have the model, open weight allow you to use. We also provide the training framework so that you can take this open model and your own data and push train to something more tailored for your use case.”
As AI moves beyond the cloud and into robots, vehicles, and other physical systems, new approaches to models, simulation, and inference are emerging. Daniel and Chris are joined by Ming-Yu Liu, Vice President of Cosmos Lab at NVIDIA, who shares his perspective on open models, world models, and the future of physical AI. They explore why open models matter for innovation, how world models can help AI understand and simulate the physical world, and what it could take to build increasingly capable physical AI systems. Featuring: Ming-Yu Liu – LinkedIn https://www.linkedin.com/in/mingyuliu/Daniel Whitenack – Website https://www.datadan.io/, GitHub https://github.com/dwhitena, X https://x.com/dwhitenaChris Benson – Website https://chrisbenson.com/, LinkedIn https://www.linkedin.com/in/chrisbenson, Bluesky https://bsky.app/profile/chrisbenson.bsky.social, GitHub https://github.com/chrisbenson, X https://x.com/chrisbensonLinks: NVIDIA Cosmos https://www.nvidia.com/en-us/ai/cosmos/Sponsors: Midwest AI Summit: Join AI practitioners on October 15 in Indianapolis for practical sessions, hands-on discussions, and real-world AI solutions. Use code PracticalAI20 to save 20% on your registration. https://midwestaisummit.com/#ticketsPrediction Guard: A self-hosted AI control plane for running agents in high impact environments. predictionguard.com/practicalai https://predictionguard.com/practicalaiResources and Events: Register for upcoming webinars here https://practicalai.fm/webinars! Prior Webinars from our partner Prediction Guard https://www.youtube.com/playlist?list=PLRpRdFmBfdF6boDgAD3nNaLm8Yx4KN2VtMidwest AI Summit 2026 https://midwestaisummit.com/
7,238 words · 4 speakers
Speaker names marked are inferred from speaking time and the show’s known hosts — they are not voice-verified.
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