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Health Experts Reveal What’s REALLY Making You Sick | Roundtable

The Dr. Josh Axe Show

Hosted by Josh Axe

1h 59m
Transcript

Original podcast

Summary

Written by a model from the transcript; not yet reviewed.

This episode features a health roundtable discussion on cellular medicine, metabolic health, and the foundational role of faith and stress management in overall wellness. The participants discuss how cellular dysfunction drives chronic illness, the importance of addressing root causes like insulin resistance and cortisol rather than just treating downstream organ symptoms, and the impact of lifestyle factors such as sleep and nutrition. They also explore the integration of spiritual well-being and mindset into physical healing, offering practical insights for long-term health and vitality.

  • Prioritize sleep and circadian alignment, as sleeping less than six hours significantly spikes insulin and inflammation. 23:10
  • Incorporate strength training and walking to efficiently increase mitochondrial density and support longevity. 1:13:01
  • Focus on bio-individuality and personalized nutrition rather than adhering to rigid, dogmatic dietary extremes. 1:30:12

Chapters

  1. 0:00
    Introduction and Podcast Premise

    Josh Axe opens the episode, setting the stage for a roundtable on cellular health and the hidden causes of sickness.

  2. 1:42
    Book Promotion and Health Resources

    The hosts promote their book *Heal Your Cells* and explain how listeners can access bonus content and resources.

  3. 3:12
    Defining Cellular Medicine and Hormonal Balance

    The discussion shifts to explaining cellular medicine, the importance of insulin and cortisol, and how fixing these hormones can restore overall health.

  4. 8:27
    Early Life Factors and Menstrual Health

    The panel explores how early onset of menstruation and childhood insulin resistance can accelerate cellular aging and increase disease risk.

  5. 12:30
    Blood Panel Indicators of Organ Aging

    They detail specific blood markers—such as APOB, insulin, and inflammatory proteins—that reveal which organs are aging faster and how to interpret them.

  6. 23:00
    Practical Strategies for Vagal Tone and Stress Reduction

    The hosts share non‑medicinal techniques—breathwork, gargling, vagal nerve stimulation—to lower cortisol, improve sleep, and support cellular repair.

  7. 23:57
    Sleep, Circadian Rhythm, and Hormonal Health

    The conversation turns to the critical role of sleep quality, circadian alignment, and cortisol spikes in driving insulin resistance and overall cellular dysfunction.

  8. 41:00
    Trauma, Faith, and Long‑Term Healing

    They discuss how unresolved childhood trauma, faith practices, and journaling can break the plateau of chronic disease and promote lasting cellular health.

  9. 44:46
    Morning Quiet Rituals for Spiritual Connection

    The hosts discuss the importance of early morning stillness and walks to connect with God and reduce stress.

  10. 45:51
    Vagal Tone and Sleep Quality

    Exploration of how improving vagal tone and nutrition can lead to better sleep and reduced anxiety.

  11. 47:17
    Messenger vs. Message in Spiritual Practice

    A conversation about how the way we communicate with God affects our spiritual experience.

  12. 48:36
    Foundations of Mind, Body, and God

    The panel emphasizes that true health requires nourishment of mind, body, and spirit, not just physical interventions.

  13. 58:41
    Peptides: Regulation, Market, and Safety

    Discussion of the current state of peptide therapies, regulatory challenges, and the need for quality control.

  14. 1:10:00
    Integrative Cancer Care vs. Conventional Medicine

    Debate over the benefits of combining conventional treatments with natural therapies for cancer patients.

Highlights

  • 1:08

    Childhood Trauma and Plateausinsight

    Unresolved childhood trauma often underlies healing plateaus, continuously replaying negative self-beliefs that maintain a state of high stress.

  • 6:18

    Cellular Aging and Disease Riskdata

    A Stanford study cited in the discussion reveals that one in five people have organs aging more rapidly than others, significantly increasing mortality and disease risk.

  • 13:10

    Insulin Resistance and Cardiovascular Healthinsight

    Insulin resistance is highlighted as a leading driver of heart attacks and strokes, requiring a look at optimal metabolic markers beyond standard reference ranges.

  • 18:12

    The Mechanism of Insulin Resistanceinsight

    Insulin resistance occurs when cellular receptors become deaf to insulin, preventing glucose from entering cells and leaving inflammatory sugar in the bloodstream.

  • 33:19

    Toning the Vagus Nervestrategy

    Active and passive vagal toning practices, such as breathwork and gargling, help regulate the nervous system and improve parasympathetic rest.

  • 53:37

    Faith and Mortality Ratesdata

    Regular faith practice and community involvement are associated with a significant decrease in all-cause mortality and inflammatory markers.

  • 1:13:01

    Weight Training for Mitochondriastrategy

    Weight training is presented as the fastest way to increase mitochondrial mass in muscle tissue, which is vital for metabolic health and aging.

Quotes

  • “Really what it is, is actual cellular dysfunction that's going on here.”
    Unnamed speaker · 0:03
  • “If you can fix those two hormones, every other hormone would go back to where it should be.”
    Josh Axe · 0:09
  • “Sleep is not a luxury. It's a mandate on our health.”
    Unnamed speaker · 0:27
  • “The amount that your insulin spikes from less than six hours of sleep is just wild.”
    Josh Axe · 0:23
  • “We have such a hubris and arrogance today because we need a randomized control trial.”
    Unnamed speaker · 0:55
  • “When you connect with God, gratitude comes first. When you have that gratitude, you're able to appreciate everything and then deliver. You can be healthy. When you give to others, you get back tenfold.”
    Unnamed speaker · 50:51
  • “People that are again, the question was like, people that are still like against people in functional medicine.”
    Unnamed speaker · 1:07:50
  • “I think people that are again, the question was like, people that are still like against people in functional medicine.”
    Unnamed speaker · 1:07:50
  • “I'm trying to work on that myself. And I've been stressing to people like, look, there's some people that I love.”
    Unnamed speaker · 1:27:31
  • “And I think that might be just as bad for them or worse than certain times seed oils.”
    Josh Axe · 1:30:46
  • Heal Your Cells 1:42–2:26
  • My Blood Work 22:10–22:38

About this episode

Your hormones, your sleep, your stress, your diet — they may all be affecting your health at a much deeper level than you realize. Dr. Josh Axe sits down with functional medicine expert Dr. Will Cole and fitness and biohacking educator Dylan Gemelli for a no-holds-barred roundtable on what may actually be driving chronic disease, accelerated aging, hormonal dysfunction, and poor metabolic health — and why healing may need to start at the cellular level. In this episode, we learn why Dr. Axe and Dr. Cole believe cellular health could change how we approach chronic disease — and how to identify which systems in your body may be aging faster than others. Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism — plus a 1-hour consultation with a Senior Health Advisor! → http://mybloodwork.com Disclaimer: The bloodwork our team runs at mybloodwork.com covers a handful of the biomarkers listed in the guide above — including critical thyroid and metabolic markers — plus a 1-hour consultation with a Senior Health Advisor, but does NOT cover all 25. You will want to consult your primary or functional doctor for the entire list. Thank you to our sponsors! Sunlighten Sauna → https://get.sunlighten.com/axepodcast Manukora Manuka Honey → https://manukora.com/axe Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube → https://www.youtube.com/@drjoshaxe?sub_confirmation=1 🎧 **Early Access!** Our listeners enjoy every episode before anyone else! Tune in below and join our exclusive group of listeners → Spotify → https://bit.ly/DrJoshAxeSpotify Apple Podcasts → https://apple.co/3JDvWcS Order our NEW BOOK, *Heal Your Cells* → healyourcellsbook.com Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → http://DrAxeDiabetesClass.com Discover practical steps you can take today to start healing your thyroid naturally → http://DrAxeThyroidClass.com If you’re ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com CONNECT WITH DR. JOSH AXE Instagram → https://www.instagram.com/drjoshaxe/ Facebook → https://www.facebook.com/DrJoshAxe/ TikTok → https://www.tiktok.com/@thedrjoshaxeshow/ X → https://x.com/drjoshaxe/ LinkedIn → https://www.linkedin.com/in/joshaxe Website → http://thehealthinstitute.com Sign up for my newsletter → https://bit.ly/4oE9Jf3 Ask Dr. Axe → http://speakpipe.com/drjoshaxe CONNECT WITH DR. WILL COLE Website → https://drwillcole.com Instagram → https://www.instagram.com/drwillcole/ Podcast → The Art of Being Well CONNECT WITH DYLAN GEMELLI Website → https://dylangemelli.com Instagram → https://www.instagram.com/dylangemelli/ YouTube → https://www.youtube.com/@DylanGemelliBiohacking Podcast → The Dylan Gemelli Podcast TIMESTAMPS: 00:00 — The Biggest Drivers of Chronic Disease 02:29 — Welcome to the Health & Longevity Roundtable 03:07 — Why Cellular Health May Be the Future of Medicine 06:10 — Is One of Your Organs Aging Faster Than the Rest? 08:22 — How Early Do Health Problems Really Begin? 12:30 — The Blood Markers That Could Reveal Heart Disease Risk 18:12 — What Insulin Resistance Actually Means 19:59 — The 2 Hormones That Can Throw Everything Off 22:58 — The Surprising Connection Between Sleep & Insulin Resistance 25:10 — “I’ll Sleep When I’m Dead” Is Destroying Your Health 31:32 — Waking Up at 3 A. M.? Cortisol May Be the Reason 32:43 — How to Lower Stress & Support Your Vagus Nerve 37:18 — How Your Mind & Nervous System Affect Your Health 41:32 — Can Childhood Trauma Keep You From Healing? 43:55 — Forgiveness, Faith & the Nervous System 48:11 — Why Dylan Believes Health Starts With “Mind, Body & God” 51:11 — Can Faith Actually Help You Live Longer? 58:35 — The Truth About Peptides & Where Medicine Is Headed 1:03:29 — Are Peptides Overhyped or the Future of Health? 1:05:31 — Conventional vs. F

Transcript

0:00
1:59:30

24,947 words · 3 speakers

Speaker names marked are inferred from speaking time and the show’s known hosts — they are not voice-verified.

Topics

  • Palsetto
  • LP little a
  • Peanut Butter
  • Mint Chip Ice Cream
  • Apollo Neuro
  • Neuropod
  • Nature
  • Sourdough Pizza
  • Heal Yourselves
  • Collagen

Page updated · transcript and summary are machine-generated