We Can Detect Cancer Years Earlier—So Why Aren’t We?

Most of medicine is built around snapshots. You feel something, you test for it, and by the time you find it, you’re already behind. But what if the problem isn’t the test—it’s how we use it? In this episode, I sit down with physicist and imaging pioneer Dr. Daniel Sodickson, Chief Medical Scientist at Function Health and author of The Future of Seeing. We break down why tools like MRI are shifting from one-time scans to something far more powerful: tracking your health over time. Watch the full conversation on YouTube, or listen wherever you get your podcasts. In this episode, we cover: • Why waiting for symptoms puts you behind—and how to get ahead • What an MRI can reveal about your body that bloodwork can’t • How tracking your health over time helps you catch problems sooner • Why having a baseline could change the way you make health decisions • What it means to shift from reacting to disease to actually predicting it When you stop looking at a single result and start looking at patterns, you can catch changes earlier, reduce false alarms, and better predict where your health is headed. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by BON CHARGE, Maui Nui, Sunlighten, Paleovalley, Fatty15 and BIOptimizers. Head to boncharge.com/hyman and use code HYMAN for 15% off. Go to mauinuivenison.com/hyman to claim your free 6-pack of their Wild Axis Venison Jerky Sticks. Visit sunlighten.com and use code HYMAN to save up to $1600 today! Head to paleovalley.com/hyman to save 15% off your first order today. Head to fatty15.com/HYMAN today and use code HYMAN for 15% off your 90-day subscription Starter Kit. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. (0:00) Introduction and overview of modern medical imaging (3:26) Discussion with Dr. Daniel K. Sodickson begins (3:45) Full body MRIs: Benefits, risks, and the inspiration behind "The Future of Seeing" (7:52) Extending senses and paradigm shifts in imaging technology (14:55) Longitudinal imaging and its benefits (19:17) Future of personalized health data and imaging technology (23:54) Addressing information overload and reducing false positives through AI (28:33) Cost, accessibility, and innovations in imaging techniques (32:00) Vision for ubiquitous and continuous health scanning (33:30) Imaging vs. blood work: Comprehensive health assessment (35:29) Real-life examples and early detection through imaging (39:27) Historical context and real-time health data collection (41:46) Who should get baseline MRIs and scan frequency (47:26) The everywhere scanner: Future implications and cancer detection (52:35) Medical intelligence and transforming health monitoring (57:47) Preventive measures, early detection, and course correction (1:00:30) Medical intelligence labs and the future of healthcare (1:03:32) Future of personal data-driven healthcare and closing remarks

Speaker names marked ? are inferred from speaking time and the show’s known hosts — they are not voice-verified.

• 0:00Dr. Mark Hyman?

  How should we really think about imaging today?

• 0:02Speaker 01

  These miraculous devices we've built are important to understand because they're going to change our lives. Maybe we don't need to wait for a doctor to have already found a problem.

• 0:11Dr. Mark Hyman?

  I kind of want to talk about this whole idea of false positives, which is something that people will push back on.

• 0:16Speaker 01

  I think everybody should have a baseline.

• 0:17Dr. Mark Hyman?

  You talked about this moment we're in, which is comparable to the invention of the telescope, not just an incremental change, but more of a quantum change.

• 0:24Speaker 01

  Wait a second, if we can see this stuff, maybe we don't need to wait for a doctor to have already found a problem. And I think that's this cusp that we're on where medical imaging is really changing.

• 0:34Dr. Mark Hyman?

  My guest today began his career at Harvard and MIT, spent years as chief of innovation in radiology at NYU, and has developed imaging technologies used to guide the care of billions of people worldwide. He's now chief medical scientist at Function Health. This is Dr. Daniel K. Sodikson. A few weeks ago, I had a fall while riding my bike and I ended up with some pretty good road rash on my face. It reminded me how powerful some of our body's natural healing tools can be when we support them with the right things. Now, one of the things I discovered during my recovery was red light therapy, which has been studied for its ability to support cellular energy and healthy cellular responses. Now, that's why I've been using the red light face mask from Bon Charge, a wellness brand

• 1:16Dr. Mark Hyman?

  that makes science-backed tools designed to help you optimize everything from sleep and recovery to energy, circadian rhythm, and skin appearance. Their red light face mask combines both red and near-infrared light, which penetrates deeper into the skin to support skin elasticity, texture, tone, and improve overall skin appearance. It's incredibly easy to use. I just wear it for about 10 minutes while winding down the evening. It's lightweight, comfortable, and completely non-invasive. Bon Charge ships worldwide, offers free shipping on the red light face mask, offers a 12-month warranty, and it's even HSA and FSA eligible. Upgrade your routine. Head to boncharge.com/hyman and use the code HYMAN for 15% off. That's B-O-N-C-H-A-R-G-E dot com slash Hyman and use the code HYMAN.

• 2:02Dr. Mark Hyman?

  There's a principle in functional medicine I talk about a lot. What your food eats matters. The nutrients in animal foods are shaped by the environment those animals live in and the plants they eat. When animals forage in the wild, that nutrition ultimately becomes part of the meat that nourishes your body. And that's one reason I love Maui Nui Wild Axis Venison Jerky Sticks. They start with wild Axis deer on Maui that roam freely and forage on hundreds of native plants growing in volcanic soil. That natural diet helps produce meat that's rich in bioavailable protein, iron, B vitamins, and key nutrients that support energy and muscle health. And that matters, especially for women, because maintaining muscle is essential for metabolism, bone health, and healthy aging.

• 2:42Dr. Mark Hyman?

  Each stick has 10 grams of protein with only 55 calories, making it a great option after a workout, between meetings, or on travel days when you need real food that supports performance nutrition. They've also become an easy snack to throw in a bag when kids are heading to sports practice and need something quick, nourishing, and delicious. Picky eaters love these sticks, benefiting everybody in the family. Right now, Maui Nui is offering Dr. Hyman Show listeners a free six-pack of their venison jerky sticks with your first order. Just go to maui nui venison dot com slash Hyman to learn more today. That's M A U I N U I venison dot com slash Hyman and head over today to claim your free venison stick starter pack while supplies last. Dan, welcome to the podcast. Thank you so much, Mark.

• 3:27Dr. Mark Hyman?

  It's great to be here. I'm just in awe of you. As I was preparing for this podcast, I was like, wow, this dude's got quite a pedigree and he is rethinking how we think and apply imaging. And we're going to talk about that today, which is this sort of new craze of full-body MRIs. What's to deal with it? Should we be doing it? What are the benefits? What are the risks? What are we looking for? We're going to cover all of it and we're going to talk about how to be proactive about your health. And we're going to talk about some of the changes in AI and medicine and some of the things that are happening on the horizon that are pretty sci-fi and wild out there, like maybe MRIs everywhere in your chair, in your bed, whatever. I don't quite get it, but you went to Yale undergraduate, studied physics, you got your

• 4:07Dr. Mark Hyman?

  humanities bachelor's in humanities as well from Yale, then you got your Harvard Medical School degree, MIT degree in physics, PhD in physics. I'm like, You've kind of been around. You were the head of MRI imaging at Beth Israel Deaconess Medical Center at Harvard, and now we're working together, which is so amazing. So for those of you listening, Dan and I are part of a company called Function Health. You might have heard me talk about it on the podcast. Dan is the Chief Science Officer. I'm the Chief Medical Officer, and together we're co-directors of what's called the Medical Intelligence Lab. And we're going to talk about what that is, what it means, and why you need to care about it, and how it applies to you and your body and your health and

• 4:48Dr. Mark Hyman?

  your long-term outlook for well-being and how you can live 100 healthy years with proactive healthcare. And that's what we're about. It's really empowering you with the data, the information, the knowledge to actually live a long, healthy life. And do you feel good now? I always say, want to feel 100% and live 100 healthy years. So that's the goal. I want to sort of zoom out. You just wrote a book, just came out in October, The Future of Seeing, and it's really about the lenses we look at the world through, from the macrocosmic world of stars to the microscopic world of cells and microbes, to all the imaging that we now have access to. We're just extending our capacity and our vision. And I'm sort of curious about what inspired you to write this book? What are you hoping people understand

• 5:29Dr. Mark Hyman?

  from it? And how is sort of our ability to see changed over human evolutionary biology?

• 5:38Speaker 01

  Great question, Mark. And first of all, let me just say the awe is mutual. But no, the reason I wrote the book was that there's this sort of weird paradox in imaging now. We lead more imaged lives than we ever have, right? I mean, you can't walk down a street without being imaged by a whole series of cameras.

• 5:58Dr. Mark Hyman?

  That's right.

• 5:58Speaker 01

  You're imaged from in utero on, and yet the mechanisms of imaging are more hidden than ever. How many people actually understand how an MRI machine works or a radio telescope works? So imaging kind of has an image problem. And what I wanted to do was give imaging back to people, to connect it to the biological vision that we evolved, to remind people that we're actually all creatures of imaging and these miraculous devices we've built. Are important to understand because they're going to change our lives.

• 6:29Dr. Mark Hyman?

  We really only understand the world through our senses, right? And the ability to extend our senses to look under the skin is pretty remarkable. I mean, vivis section, which is the human, the section of the body, was done in some, you know, ancient cultures, but often was not because the body was considered sacred. Like in Chinese medicine, they never did that. And so they, they would kind of have to intuit how things worked without actually knowing anything about what's happening on the inside. And now, you know, we had the sort of crude imaging with X-rays back to the turn of the last century, you know, and people used to go get shoes and they get X-rays to kind of look at their feet, which was a bad idea.

• 7:06Speaker 01

  Bad idea.

• 7:07Dr. Mark Hyman?

  Or people had like radiation, X-rays for their acne on their face. Bad idea, caused a lot of cancer. So we've kind of had this sort of interesting history. And, and, and you know, I'm old and older than you, but I, you know, MRIs were kind of a new thing when I was in medical training and was in the early eighties. And it was just kind of a coming on the horizon, our ability to kind of look deeper into things. We first had X-rays and then we had CT scanners, we have ultrasounds, we have MRI machines. There's other kinds of imaging out there as well. How, how should we really think about imaging today? Because we see, you know, a lot of kind of hype out there. Kim Kardashian goes to get a scan and everybody's like, oh, wow, you know, what is this about? I want a full body MRI. How should we be thinking about this?

• 7:52Speaker 01

  So I think first of all, you're absolutely correct that extending our senses is a really fundamental thesis of imaging. And I would argue that every time we extend our vision, we invariably expand our minds. We saw that from the Copernican revolution.

• 8:11Dr. Mark Hyman?

  Yeah.

• 8:11Speaker 01

  Basically, it was the results of imaging devices that forced us to reckon with the fact that we're living alone on this little rock in this vast universe. X-rays completely took the world by storm, like you said, as did tomography later on.

• 8:28Speaker 01

  And so I

• 8:29Dr. Mark Hyman?

  Tomography is what?

• 8:30Speaker 01

  And forgive me, yes, tomography.

• 8:32Dr. Mark Hyman?

  Because none of us speak physics.

• 8:33Speaker 01

  Exactly. It's CAT scans, MRI machines, PET scans.

• 8:39Dr. Mark Hyman?

  Complicated assembly of images from different sources.

• 8:41Speaker 01

  And really what it means, it comes from a weird Greek root, which stands for the writing of slices. And really, that's what all of these modern imaging devices are doing. They're slicing through the body every which way without making a single cut. And I think when you, you know, you ask how to think about modern imaging, that's really what modern imaging is doing. It's capable of basically dissecting the body without ever cutting into it. And it's become this integral tool in medicine that people use to diagnose disease, to guide surgery, all of that. But as you said, its use is starting to change. And people are realizing, wait a second, if we can see this stuff,

• 9:25Speaker 01

  maybe we can see it early. Maybe we don't need to wait for a doctor to have already found a problem. And I think that's this cusp that we're on where medical imaging is really changing.

• 9:36Dr. Mark Hyman?

  Yeah, because most doctors will only diagnose you when you have a symptom. Like, oh, I have a stomach pain. Maybe we should get an MRI of your stomach. Or I've got a head pain, or I'm losing vision, or I can't walk. Maybe we should get an MRI of your brain. And what you're suggesting is that that might not be the right way to think about things. It's a proactive, preventive way to think about imaging. And, you know, we talk a lot, you know, in the space around what we call P4 medicine, which is Lee Warhol's vision, who's an assistant biologist of how we need to think about health, which is preventive, it's predictive, meaning you can kind of predict where you're going. It's personalized, so really different. And it's participatory, meaning we all have to kind of participate in our health, not just passive activity.

• 10:19Dr. Mark Hyman?

  What's, what's happening now is, is that the speed of imaging, the application of AI to imaging, innovations in imaging, the deflationary cost of imaging. Are all starting to got a hit at the same time. And you talked about this sort of moment we're in, which is comparable to the invention of the telescope. In terms of our understanding of like the technological changes, not just an incremental change, but more of a quantum change. Can you kind of unpack that? Because I think most of us just think, oh, we go to the doctor, we get imaging and we got a symptom. But you're talking, and even me, I'm a doctor and I am still curious about, because I don't understand what you're thinking about how this change is so revolutionary.

• 10:55Speaker 01

  Let me attack that basically through a bit of a personal story. Cause I started out in kind of a traditional way of thinking about imaging. This is the tool you use to open up the body for inspection by doctors. Once we want to find something wrong. And what happened is over time, as I worked more and more on optimizing, for example, these MRI machines, making them faster, making them better. I realized that a lot of the time they were being used to chase after symptoms. That we were telling people remarkable, important information, but we were telling them too late. Like, oh gee, I'm sorry, you have an advanced invasive cancer.

• 11:35Speaker 01

  Is it any surprise that radiology departments don't get as many philanthropic donations as, say, surgery departments? We're the people who tell you you're sick.

• 11:43Dr. Mark Hyman?

  Right.

• 11:44Speaker 01

  And then we hand over to someone else to fix it.

• 11:46Dr. Mark Hyman?

  That's right.

• 11:46Speaker 01

  And it started dawning on me that maybe there's a way we can use these tools, our kind of best tools for visualization first, rather than last. But that involves overcoming a few obstacles. First of all, they're big and expensive, right? So a lot of people say, oh, we can't do imaging, you know, early because it's going to rack up medical costs. Then also we have this weird problem that we see too much. If you put somebody in an MRI machine, you're going to find a little ditzel here or there. There's always going to be something you find, which raises a question. And so this raises the whole big question of false positives.

• 12:27Dr. Mark Hyman?

  Meaning that you see something on there that looks like something, but it's really nothing.

• 12:31Speaker 01

  Exactly.

• 12:32Dr. Mark Hyman?

  And then you worry, you get worried about it and then you chase down and it.

• 12:36Speaker 01

  That's right.

• 12:36Dr. Mark Hyman?

  Worry and costs and interventions and.

• 12:39Speaker 01

  All of those things and, and, and those are the entirely understandable reasons people haven't used imaging proactively in the past for fear of running up those costs and creating that anxiety and giving people sort of these unnecessary tests. But as a physicist and a designer of machines, I started wondering, well, can we drive those false positive rates down? They're not God given, right? They're not somehow attached to the devices. They have to do with the way we use the devices. And so what occurred to me after some time is, well, the problem is that we're not actually putting these images in context. We're used to getting these images and then looking at them that day, seeing what we see

• 13:24Speaker 01

  and saying, ah, you know, we're the, we're the wise philosophers, you know, peering at the images and saying, well, this is your future.

• 13:32Dr. Mark Hyman?

  Yeah.

• 13:33Speaker 01

  But if you want to predict the future, you should know the past. So what if we had previous images? What if we had a whole series of images over time? Then we could say, you know what? I see this thing here, but I know it's normal for you. And in fact, radiologists do this all the time. If they see something and it hasn't really changed from last time, they might say, you know what? I'm not too worried. Come back in six months, come back in a year.

• 13:57Dr. Mark Hyman?

  We call that an incidentaloma.

• 13:59Speaker 01

  Yeah, that's right. That's right. But we can actually understand incidentalomas if we've seen them before. And so this notion of using imaging over time and interpreting it in context became a kind of a revelation for me.

• 14:16Dr. Mark Hyman?

  Yeah, it's, it's kind of a, it's kind of a big leap, right? Which is, it's so outside of our traditional thinking in medicine, which is to minimize diagnostic test, to rely on history and to kind of wait until people are symptomatic or as you said, in advanced stages of disease before we actually do something, which is kind of too late. It's kind of getting too late to the party and then you're, you often can't really help people or they have to go through a lot more ordeal and rear in terms of treatment and expense and pain and suffering. What you're suggesting is that there's a way to use these technologies in a different way.

• 14:53Speaker 01

  That's right.

• 14:53Dr. Mark Hyman?

  Right?

• 14:54Speaker 01

  That's absolutely right.

• 14:55Dr. Mark Hyman?

  And to use them in a way that measures things over time in a longitudinal way. And allows you to see the change over time. And then the imaging becomes faster, smarter, better. Because it keeps tracking your biology over time, just like a lab test.

• 15:09Speaker 01

  Yes.

• 15:10Dr. Mark Hyman?

  We do, we do this with lab tests when we check your blood sugar and you know, maybe it's rising, we'll then intervene early, hopefully, or you'll see your PSA, which is a prostate cancer test. That, you know, may be slightly creeping up. And we watch it and we can see over time how the change happens. We do this, but in imaging, that's not something that really is done. And you're suggesting that's something we should do.

• 15:32Speaker 01

  Absolutely. And in fact, it's interesting, you say that it's not done because traditionally it hasn't been, but quietly, there's been this paradigm of imaging surveillance. Say for tumors that has been building up in medical circles and Hasn't necessarily been getting a lot of press, but you know, if I go in and I have a moderate risk for prostate cancer. I may get An MRI every year. And be followed. That MRI will be interpreted in context. And when there's a sudden change in the findings, then my doctor might say, oh, you know what? We better go to biopsy, we better check it out. So people have actually realized this paradigm.

• 16:14Speaker 01

  But because imaging, people tend to think of as a snapshot. Somehow that perspective hasn't pervaded and people still say, well, you don't want to do it in people of low risk. You know, only do it in people with well established high risk. And my argument is, but most people out there in the world Don't have a known risk. Shouldn't we be casting a protective net around them too?

• 16:39Dr. Mark Hyman?

  Yeah.

• 16:39Speaker 01

  If we can figure out how to make sure we're not, you know, raising a false flag all the time.

• 16:44Dr. Mark Hyman?

  Now, if you know me, you know, I've spent a lot of time in my own life, learning how important it is to support the nervous system and get restorative sleep. In today's world, many of us are stuck in constant fight or flight, always on, always stress mode. And that's hard on the body and it makes it hard to recover, to repair, to sleep deeply. And one tool that's non-negotiable for me is my sauna time. Stepping in my sauna helps shift the body into parasympathetic mode, the rest and repair state where detoxification, recovery, and hormone balance can work most efficiently. It also improves circulation while helping calm the nervous system. And many people notice that regular sauna sessions improve relaxation and sleep quality. For me, an evening sauna is a signal to my body to slow down, letting me rest more deeply.

• 17:28Dr. Mark Hyman?

  And Sunlighten's Impulse Sauna even has six custom programs like relaxation and detoxification, so you can step in, choose a session, and let it do the work. If you want to support your sleep, recovery, and nervous system, check out Sunlighten today by visiting sunlighten.com and use the code HYMAN to save up to $1,600. That's sunlighten, S U N L I G H T E N, dot com, and use the code HYMAN.

• 17:55Dr. Mark Hyman?

  Every day, our bodies face stress, inflammation, and the challenges of modern life. And one of the simplest ways to support your health is with turmeric. It's a spice used for centuries in cooking and traditional medicine. The key compound in turmeric is called curcumin, a polyphenol that research shows supports the body against conditions like cancer, cardiovascular stress, and neurodegenerative diseases like dementia. It can also help with inflammation, metabolic balance, joint comfort, even mood. Most turmeric supplements contain only isolated curcumin, which isn't always well-absorbed. Paleo Valley's Turmeric Complex is something different. It uses whole-food turmeric with over 200 beneficial compounds, plus organic ginger, rosemary, and cloves. Gentle heat and black pepper improve absorption,

• 18:40Dr. Mark Hyman?

  so your body can actually use the curcumin. With thousands of studies supporting turmeric's role in immune function, joint comfort, and brain health, Paleo Valley's Turmeric Complex is an easy, natural way to support your overall wellness and every single day. So head over to paleovalley.com/hyman today for 15% off or use the code HYMAN at checkout. That's P A L E O valley.com/hyman for 15% off and use the code HYMAN. It's interesting. I kind of want to talk about this whole idea of false positives, which is something that people will push back on. And I wanted you to kind of explain this because you've written a lot about it and you've talked a lot about it.

• 19:17Dr. Mark Hyman?

  And I think we're touching on it now. And I think it's important because my personal belief is that with the radically deflationary costs, with the potentially ubiquitous nature of these imaging technologies, which we'll talk about soon, with our ability to collect large personal health data sets from your lab testing to your medical history, to gathering your EMR, to wearables, to all the omics, your genome, your podium, your microbiome, your metabolome, to gathering imaging data, be able to aggregate that in a platform, a technology platform, that allows you to track your biology over time and putting your biology online is a revolution that we've never seen in medicine before.

• 20:00Dr. Mark Hyman?

  You and I, you know, as doctors, you know, if we see patients, we get, and I had a patient like this yesterday, who's got a chart from here and a chart from there and a lab from here and a lab from there and imaging test from there and imaging test from there and a scope from here and a scope from there. And I'm literally, you know, having to aggregate all this. I'm having to gather all this data. It takes, you know, hours of my time or my team's time to get it ready for me. It's not very user friendly for the doctor or for the consumer or patient. And what we're seeing now is with Function Health, which is I think why you've kind of left your big job at NYU. You had a big, big fancy job there and joined Function Health as a chief science officer is because you see the future.

• 20:42Dr. Mark Hyman?

  I mean, you wrote a book called The Future of Seeing and you see the future in a different way, which is where medicine is going, which is a proactive, longitudinal, large personal health data set, tracked over time, that can understand that biology just doesn't change overnight. It's a continuum of dysfunction that's slow and progressive over many, many decades sometimes that we now can see. For example, we can tell on imaging, and I mean, you can talk about this, changes that can predict. Alzheimer's decades, decades before you forget your keys or you have a symptom. Should we be doing that? And people are high risk, you know, there's, there's ways of actually seeing changes that, that are really important on, on all these data sets, whether it's your blood

• 21:26Dr. Mark Hyman?

  sugar, your blood pressure, or your cholesterol, which we're kind of familiar with, or whether it's, you know, other things like, you know, if you have a, a low vitamin D, maybe you're not symptomatic. And, and by tracking stuff over time, we can start to really understand the human body in a way we've never done before. I'm just setting this conversation up because I want to dive into this, this false positive conversation. I had a conversation with a friend of mine the other night. She's like, I don't want to know. I've got Alzheimer's in my family and I don't want to know if I have the gene for Alzheimer's. I'm like, I explained to her, look, you might have a, a risk gene. So APOE four, which is a risk gene for Alzheimer's is common. And, you know, if you have a, a this gene

• 22:07Dr. Mark Hyman?

  or two copies of this gene from both your parents, you're in a much higher risk of getting Alzheimer's. It doesn't mean you're going to get it. It means you're at higher risk. And then you go, okay, I know I can be prude about every other single thing that we know may influence the risk of getting Alzheimer's from my diet, to my exercise routine, to my sleep management practices, to my stress regulation, to the right nutrient levels that I need to make sure I maintain the right hormone levels I need to maintain if I'm a woman or a man. Like there's so much you can do, but she was like terrified to know. I'm like, no, no, this is not a predestiny. This is a predisposition. And so in, in that way, I think we can kind of remove some of the fear by realizing this with our

• 22:49Dr. Mark Hyman?

  scientific knowledge now, there's such a moment for empowerment around knowing your own data. You know, I'd love, given that sort of background, and then I want to sort of dive into the medical intelligence framework, because I think the longitudinal scanning is sort of the answer to the false positives, and maybe there's more, but it's also the answer to understanding your health in a better way. And it's understanding how to apply the advances in AI and medicine and science to you personally through what we call medical intelligence in our medical intelligence lab at Function Health. So to take us through, you know, a skeptic's view, I'm, I'm like Dr. Harvard here, and I'm like, oh, you know, this is expensive. It's, it's too much to do. You're going to get all these red herrings. You're going to chase down all these things. You're going to cause

• 23:31Dr. Mark Hyman?

  unnecessary suffering and worry and anxiety. Why should everybody get an MRI every year? Like a full body. I do it. You do it. We do it for ourselves. You know, we want it for our families. I just ordered on one of my staff members tonight because I think he needs it. But like, why, why is this so important? And how do we get out of this, this sort of fear mode or these worry mode about, about too much information?

• 23:54Speaker 01

  Even that framing is interesting, isn't it? Too much information, right? I mean, there's sort of this sense that, oh, my goodness, we'll see too much. We won't know what to do with it. So let's just close our eyes. And there was, there was a time when that was appropriate, right? I mean, people often say in medicine, if a test isn't going to influence your treatment, your plan, your decision making, then don't do the test. And that's actually entirely legitimate. But as you were gesturing towards, we live in a very different time than even just a few years ago.

• 24:30Dr. Mark Hyman?

  Yeah.

• 24:30Speaker 01

  Now we live in a time of big data and AI, when we can collate a large collection of data, and we can use AI to connect it over time, to look for subtle changes, for subtle patterns, at a scope that's hard for a single human mind to do. And so I think, you know, my recommendation isn't just go out and get a traditional MRI and have people read it in the same way they always did, looking only at today.

• 25:00Dr. Mark Hyman?

  Yeah.

• 25:01Speaker 01

  My recommendation is establish a baseline for yourself.

• 25:05Speaker 01

  And I think it's up to us in medical intelligence and up to the broader community to figure out how we deal with this multifaceted data. And I'll give you just a couple of examples coming from work in my NYU lab before I, I made the jump to function. So we took an AI model and trained it to predict your risk of clinically significant prostate cancer in five years' time, based on today's images.

• 25:32Speaker 01

  Did an okay job about as well as humans. Huge false positive rate, like 64% false positives. So not very good.

• 25:40Dr. Mark Hyman?

  On the MRIs for prostate.

• 25:42Speaker 01

  On the MRIs for prostate cancer. So not a very good prediction five years out. But then we did something interesting. We took that same model and we fed it last time's images. And a year before, and a year before, and we also fed it some blood tests and some clinical data. And lo and behold, the more prior information and the more diverse the information we gave the model, the more the false positive rate dropped. Until it was below 10%. So an order of magnitude reduction in false positive rate, just by incorporating context. The second thing we did.

• 26:17Dr. Mark Hyman?

  So in that sense, more information helps you make better decisions.

• 26:20Speaker 01

  Exactly. So instead of gee, we don't know what to do with it. Let's close our eyes. The idea is let's incorporate everything we know. Now, we need to build the models to do it. But the example I just showed you shows that it is in fact possible. Even in a pretty simple prediction model to incorporate context. And you know, I mean, as a master of functional medicine, right? Context is everything.

• 26:43Dr. Mark Hyman?

  It's everything, yeah.

• 26:44Speaker 01

  You can't just look at one organ system in isolation. You also can't just look at one time point in isolation.

• 26:50Dr. Mark Hyman?

  Looking at the patterns in the data over time.

• 26:52Speaker 01

  Exactly.

• 26:53Dr. Mark Hyman?

  Patterns in the data over time illuminate the real issues and whether there's something to do or not to do.

• 26:58Speaker 01

  100%. As a, you know, academic or former academic, I need to say, you know, this paradigm is still evolving. So it's not like every MRI you get is going to be put in context in this way. But in the future, that's exactly what we're aiming at. We want your MRI to be, you know, hand in hand with your blood tests and your genetics and your proteomics. And all of this, because that rich context is going to eliminate many of those false positives and give you the guide you need.

• 27:30Dr. Mark Hyman?

  And that's where we're really building a function. It was a place where you can get access to your own biology. Before you had to go through this firewall of doctors and insurance companies and. You know, maybe they would order it, maybe they wouldn't order it. You you wouldn't be able to really know what's going on with your own biology. You have a dashboard for your car. Why wouldn't you have a dashboard for your body? And we're talking about establishing, you know, like a those thousand point sensors, you know, go to your, take your fancy electronic car in and they hook it up to the these machines and they just run through all these tests. And I'm like, this is amazing. We don't have that for our body, you know? And we don't have the dashboard that tells us how to navigate what's going on in our life. And so we're often at the effect of things rather than being at the cause of our life,

• 28:15Dr. Mark Hyman?

  you know, in proactive way, empowering ourselves with the knowledge, information to prevent disease and to find things early and to actually reverse things before they become problematic. One, one of the things that's also happened is the ability, I think, to to really improve the speed and the the access and the cost. So can you talk about that? Because and I remember going to get my knee. I had a knee issue because I jumped off a golf cart and I kind of tore my meniscus. And I was like, oh, my knees. So I'm going to go get an MRI. And so I I went to get MRI and it was like 2,500 bucks for my knee. And now we're talking about 4.99 or 9.99 for a whole body MRI. So how how is that taking us down the road to making this more accessible and affordable?

• 28:59Dr. Mark Hyman?

  And also, you know, how do we, how do we think about using that?

• 29:02Speaker 01

  So here's the really interesting thing. In the future, and I think it's actually pretty the near, pretty near future.

• 29:10Speaker 01

  The more we image you, the faster we can scan you next time.

• 29:14Dr. Mark Hyman?

  Is this actually the same machine?

• 29:16Speaker 01

  No.

• 29:16Dr. Mark Hyman?

  It doesn't.

• 29:17Speaker 01

  The faster and the cheaper we can scan you next time. And I'll, I'll give you one other example that came out of work from, from my lab. Basically, what we found is if we've only, if this is the first time we're seeing you, we need a requisite amount of data. We need the scanner to gather a certain number of views of the body to create that's those slices we need. But if we've seen you before, this time we trained another neural network whose job is to take those different views and assemble them into a, a set of images.

• 29:49Speaker 01

  And we tried taking a drastically reduced set of views, 20 times less data, 30 times less data than you would need for a traditional image. In other words, 20 or 30 times faster. And we found that the neural network, if it had your prior scans, could generate a perfect, high-quality image 20 to 30 times faster with 20 to 30 times less data. Why? Because we already knew the rudiments about you and your anatomy. All we needed to look for was change. So, once we have that baseline, not only can we predict your health better, but we can also scan you faster. And it turns out, another thing we tried was, what if we use worse data? What if we use data from a

• 30:34Speaker 01

  low-power MRI machine? Or maybe from an MRI machine, we might build into a seat that would otherwise give pretty lousy-looking images? We did that simulation, and we found that, actually, we can get away with much worse data.

• 30:50Dr. Mark Hyman?

  Interesting.

• 30:51Speaker 01

  If we have that prior information about you. So, once again, context is everything. If we have the context, maybe we don't need these big, multimillion-dollar tubes.

• 31:01Dr. Mark Hyman?

  Yeah.

• 31:01Speaker 01

  Once we've seen you at least once, maybe we can put something in a chair, in a bed, in a CVS, in your home, at drastically reduced cost. So, more imaging, paradoxically, allows cheaper imaging.

• 31:16Dr. Mark Hyman?

  But does you have to use the same machines? Like, Siemens, one machine, or GE, another machine? Can it kind of, how do you, how does it gather that data from the past?

• 31:24Speaker 01

  So, there's a logistical challenge of how do you bring your past images from another machine into today's machine so that it can do this? But that's just logistics. I mean, nowadays, we have, you know, digital image transport systems and so on. But what we found is, it doesn't need to be, the image doesn't need to be exactly the same last time as this time. In fact, we used different contrasts last time, and it still informs, you know, your imaging this time. So, this is actually part of something, I think you may have referred to it before, that I call the Everywhere Scanner Vision.

• 32:00Dr. Mark Hyman?

  Yeah.

• 32:00Speaker 01

  If we have enough information about you, if we've done the advanced imaging, the advanced blood testing upfront. Then for the interval scanning, maybe we can use cheap scanners. Maybe we can even use constellations of wearable devices on your clothes because all they need to do is measure change.

• 32:18Dr. Mark Hyman?

  That's amazing.

• 32:19Speaker 01

  Which means we can move healthcare not only more proactive, but also make it more continuous.

• 32:24Dr. Mark Hyman?

  Crazy. It's kind of like, what was that guy's name? Bones from Star Trek?

• 32:27Speaker 01

  Yes, yes.

• 32:31Dr. Mark Hyman?

  Tricorder?

• 32:32Speaker 01

  The tricorder.

• 32:32Dr. Mark Hyman?

  Scanner for the?

• 32:33Speaker 01

  I would just tell you, the tricorder has been like a holy grail for imagers forever, right? Because it's this tiny little handheld device. You wave it in front of something, somebody, and you get everything you need. I actually think, and I talk about this in the book, I think the tricorder is a bit of a trick. I think it's actually not its own device doing imaging. I think it has access to all of the records that Starfleet Academy had on you.

• 33:01Dr. Mark Hyman?

  Yeah.

• 33:01Speaker 01

  And all it's doing is looking for change.

• 33:04Dr. Mark Hyman?

  Yeah, that's amazing. That's amazing. So people understand that they can get blood work and know a lot about their bodies. And a lot of people have joined function as members and are learning so much. And we're seeing so much in the population that people are discovering that saves their lives from cancer, or figures out they have autoimmune disease, or figures out they have other problems that are really fixable. How does imaging differ from blood work? And what are we looking for? People are like, oh, I'm looking for my cholesterol, my blood sugar, my hormones, or my vitamin D level, or, you know, whatever, my blood count and my immune system. But what are we actually looking for? And how does it differ from blood work? And then last question, how do you, how do you think the two together are better than either alone?

• 33:49Speaker 01

  So I think blood tests give you biological and chemical context, right? It's the various biomarkers that your body is producing that tell us about the biological functioning and systems. Imaging is spatial context, right? I mean, if we were just undifferentiated bags of chemistry, then blood tests would be enough. We wouldn't need to know anything more. But we all know that bodies are sort of these complex bio weavings, and it matters what's where, when. And so imaging, as I see it, is what puts all of this chemistry in context, in spatial context.

• 34:27Speaker 01

  Which leads naturally to the question of synergy. Like you want both, right? You want to know what's where. And you also want to know what's the biological functioning in each position. And when you've got both, you sort of have this magic mixture. So what do we look for?

• 34:44Dr. Mark Hyman?

  Structure function.

• 34:44Speaker 01

  Structure function, exactly. And so what do you look for in imaging? Well, you look for tissue that's out of place, right? A tumor that might be growing where it shouldn't. You look for derangements of the brain that tell you hints of, you know, Alzheimer's disease, things like that, things that there may not be a circulating counterpart. There may not be something that was spit off and sent into the bloodstream. And so you can measure it in a blood test, but you can see it inside you. You can see it where it is.

• 35:16Dr. Mark Hyman?

  If you have an aneurysm, there's no blood test for that.

• 35:19Speaker 01

  Exactly right. I think this combination of biological, biochemical and spatial context is really, you know, cooking with gas.

• 35:29Dr. Mark Hyman?

  We are both part of Function Health and we do imaging as part of the offerings we have. I think it should be part of the, you know, ultimately just part of the thing that everybody does, which is not just the blood or but also the imaging. What are we finding? Tell us some stories about what we're finding. Cause you know, you've been working with Ezra, which was a company that became part of Function for a long time and you've seen a lot of stories and we're seeing crazy stories of people. What are people discovering and what are they finding?

• 35:56Speaker 01

  Absolutely. And I'll preface it by saying, you know, I know there are going to be some physicians out there who say, you know, any story I come out with, it's just an anecdote. It's not, it's not, you know, randomized controlled trials and so on. I'll get back to that later because I think there's an answer for that.

• 36:10Dr. Mark Hyman?

  Anecd data.

• 36:11Speaker 01

  Anecd data. But no, I mean, the obvious things clearly we have found tumors that people didn't know they had.

• 36:17Dr. Mark Hyman?

  And early before they, it kills them.

• 36:19Speaker 01

  Exactly. And that's the key. I mean, you know, our, our friend and colleague, Emi Gah, likes to say, we already have a cure for cancer. It's early detection.

• 36:28Dr. Mark Hyman?

  Yeah.

• 36:29Speaker 01

  Because most cancers, if you catch them early enough before they've become invasive. They're that much easier to get rid of with radiation, with chemotherapy, with surgery. So we have found certainly prostate cancers, brain cancers, kidney cancers at such an early stage that they weren't giving anybody symptoms. That was the whole point. But what that meant is these people could then go in for therapy right away, long before these things would have been discovered.

• 36:58Dr. Mark Hyman?

  Yeah.

• 36:59Speaker 01

  And it is saving their lives. There are any number of other kind of body areas where you can pick these things up. Ezra had a particular focus on cancer, which is sort of obvious because early means life.

• 37:11Dr. Mark Hyman?

  But we can see the change in the brain function structure.

• 37:14Speaker 01

  Absolutely.

• 37:14Dr. Mark Hyman?

  We can look at brain size changes. We can look at the structural pieces of the brain that change over time that could be linked to different diseases like dementia. We can also see, you know, interesting things in terms of body composition, fatty liver.

• 37:26Speaker 01

  Cardiovascular health, right coronary artery calcium scans have been shown actually with very good data to be predictive of cardiovascular risk.

• 37:36Dr. Mark Hyman?

  Right.

• 37:36Speaker 01

  And that we can see in a very straightforward way. Combine that with some of the cardiovascular biomarkers, and again, you're cooking with gas.

• 37:45Dr. Mark Hyman?

  Yeah, I think that's it. I think, you know, the combination is important. And I remember, I don't know if you remember that textbook we had in second year medical school called Robbins and Co. Tran.

• 37:51Speaker 01

  Oh, yes.

• 37:52Dr. Mark Hyman?

  That patho is called the pathophysiological base of disease. And I went back, I still have the my copy from like 1984.

• 37:58Speaker 01

  Me too.

• 37:59Dr. Mark Hyman?

  We have a mammogram, we have, you know, thing PSA we screen for, but like most cancers we don't even screen for. And when you combine that and those two, and I think emerging proteomic data, which is coming when proteomics are basically proteins that the body makes and these cancers spit off these proteins that we use sometimes already to detect cancer or follow progression like alpha protein or CEA, C125 for ovarian cancer. These are things that we've been using in medicine a long time, but they're used kind of late. They're used to manage the disease, used to track progress. But if you combine these and using AI, and this is the, this is the, this is the amazing thing about the data. This is, this is coming soon. There's these large, these large databases of cancer survivors,

• 38:44Dr. Mark Hyman?

  and they have biobanks where they collected their blood. They've been able to go back and say, okay, well, let's look at all the patients with lung cancer, all the patients with pancreatic cancer, all the patients with colon cancer, all the patients with prostate cancer, all the patients with breast cancer. What do they have in common? You mean, within each cancer? And then they can go back and check this blood and screen five years ago and see these, these proteins that get expressed. And they're able to, through AI, make sense of all it. Because it's like, if you've got, you know, millions of data points, in the average doctor can't, well, no doctor, even a brilliant doctor can't, like you, can't sort through all that. And so, using, like you said, big data and AI with, with our understanding of biology, we're entering a new era of medicine. This is the era of medical intelligence. That's what I'm talking about when I say that.

• 39:27Speaker 01

  I agree entirely. And I've obviously voted with my feet to that effect. Can I get back for just a second to the kind of clinical trials question? Because that is one of the things that gets thrown out a lot as a concern. Like, okay, all of this is wonderful in principle. It makes sense, but where's the data? And should we be proceeding until we have the data? And I actually want to go back to another time in history, the 1970s, when all of these tomographic imaging techniques, MRI, CT, PET, ultrasound, were being developed. Back then, the value of knowing what was where in the body was obvious.

• 40:09Speaker 01

  So there were a thousand CT scans in hospitals between 1971, when CT developed, and 1979, when the inventors got the Nobel Prize for it. There were no large-scale clinical trials showing the efficacy of seeing versus not seeing. Now, I'm not suggesting we should throw caution to the winds. We should absolutely be gathering data as we go. And in fact, big data allows us, in some ways, to do almost real-time trials as we go. But to say, listen, I'm not going to do anything until the data is there.

• 40:49Speaker 01

  I think that's one extreme of a kind of spectrum that we should be thinking about. I think there's this kind of protective instinct, which I, as, as somebody in medicine, I believe in. But I don't want to be protecting patients, protecting people from this new era that's coming. I want to figure out how we, how we make it happen as quickly as possible and measure as we go.

• 41:16Dr. Mark Hyman?

  Yeah, I mean, how do we not get ahead of ourselves? But, you know, in a perfect world, we would, we would bring the cost way down. We'd allow people to access large data sets themselves. We'd be able to track it over time. We'd be able to see where they're headed and what to do about it. And that's really what Function Health was designed to do. That's why we created the company, was to empower people to be the CEO of their own health, to be empowered to own their own data, to be able to have a data-driven healthcare and medical system, and to use big data and AI analytics to understand all this

• 41:46Speaker 01

  Yes.

• 41:46Dr. Mark Hyman?

  massive amounts of information. How many like, how many gigabytes or terabytes is like a full dense MRI bot? It's like a lot, right? You can't even sit on your computer.

• 41:55Speaker 01

  That's right. It's a bunch of gigabytes per person, per session.

• 41:58Dr. Mark Hyman?

  You know, what I, what I want to sort of have people understand is like, who should and when should somebody think about starting to get their first baseline MRI? Is it when you're 20 or 50 or 100?

• 42:11Speaker 01

  Right. Well, again, it's hard to point to a data-driven age because it varies for the particular thing you're looking for and all of that. I guess I would reframe it and say, I think everybody should have a baseline,

• 42:27Speaker 01

  a baseline scan because, you know, and okay, maybe not while the body is still developing when you're, you know, five or 12 or something, although, you know, there's some argument there too. But the whole point is we want to be able to measure change in your body. We want to be able to know what's normal. And so I think at the very least, that reference scan.

• 42:53Speaker 01

  There's no reason for that not to be done early.

• 42:57Dr. Mark Hyman?

  Like in your twenties?

• 42:58Speaker 01

  In your twenties, as long as the people who are interpreting it aren't jumping the gun and freaking out at everything they see. So the problem with that first scan is we don't yet have the context. And so there's a tendency then to follow every lead. If, and, and, and this is another sort of paradoxical thing. If we know that imaging is going to be regular, then we don't have to freak out at every finding. So in other words, we get a baseline and we say, okay, we're going to see you again in a year or two years to make sure we've established not just one point, but a trajectory.

• 43:35Speaker 01

  Even just that second scan is already going to rule out

• 43:40Dr. Mark Hyman?

  Yeah.

• 43:40Speaker 01

  most problems. So I think that, you know, we're heading to an era when people should have a baseline and a sense of trajectory

• 43:51Speaker 01

  relatively early so that we can establish this basis for change.

• 43:55Dr. Mark Hyman?

  So then how often should someone do a scan yearly? Or, I mean, for example, I'm 66. I kind of want to do one every year.

• 44:03Speaker 01

  Right.

• 44:03Dr. Mark Hyman?

  Does that make sense? But what if I'm 35? Do I want to do one every year?

• 44:08Speaker 01

  And again, the scientist in me is, is pausing because, you know, I'm not, I don't have studies to point to. But from sort of basic logic, my feeling is yes, more frequently as you get older and changes are more likely. A little less frequently when you're very young and, and changes aren't that likely. If we can, let's put it this way. If we can get the cost of something like an MRI scan down enough. And if we can make sure that we're not overcalling things, then there's no reason not to have an absolutely regular scan. Let's say two years, every two years when you're younger, every one year when you're a little older. I want, and you know, you know, with the everywhere scanner vision,

• 44:51Speaker 01

  I want imaging to be kind of an ongoing intimate part of our lives. Not this thing that we do just when we're worried. Are we sick? I want it to be the thing that tells you you're, you're still okay. Not the thing that only tells you that something's wrong.

• 45:10Dr. Mark Hyman?

  Yeah.

• 45:10Speaker 01

  I want it to be a safety net, not, you know, an end stage tool.

• 45:15Dr. Mark Hyman?

  For over 50 years, we've been told to avoid full fat dairy to protect our long-term heart and metabolic health. And in a massive turn of events, the new dietary guidelines for Americans were recently released that put full fat dairy back on the top of the pyramid. While the science around full fat dairy has been mixed, there is one consistent surprising story. C15, it's a super fat in dairy. It's emerging as a foundational nutrient that we all need to age healthier. Backed by over 100 peer-reviewed studies, Fatty 15 delivers pure, patented, and vegan-friendly C15 to strengthen our cells and reverse aging at the cellular level. The science and the quality behind Fatty 15 is why it's been a trusted must-have in my healthy aging supplement routine for years. You can head

• 45:59Dr. Mark Hyman?

  to fatty15.com/hyman today and use the code HYMAN for 15% off your 90-day subscription starter kit. That's fatty15.com, F-A-T-T-Y-1-5.com/hyman today and use the code HYMAN to get 15% off.

• 46:17Dr. Mark Hyman?

  I know you've heard me talk about the importance of getting enough protein to maintain muscle as we age, but sometimes even when you eat well, meals can leave you feeling heavy, bloated, or sluggish. Now, in some cases, it's not protein, it's your digestion. And our bodies rely on enzymes to break down protein and fats and carbohydrates so we can actually use the nutrients we eat. Now, with stress, with age, or busy lifestyles, enzyme production can fall short. And that's why I recommend mass enzymes from Bioptimizers. It contains 18 different digestive enzymes, including four times more protease than many other formulas to support the breakdown of protein, fat, and carbs. Supporting digestion can help turn meals into clean fuel, so you feel lighter, more energized, and more comfortable

• 46:58Dr. Mark Hyman?

  after eating without changing your diet. If your goals this year include eating well and feeling better after meals, well, mass enzymes is a simple way to support healthy digestion. For an exclusive offer, visit bioptimizers.com/hyman and use the code HYMAN to get 15% off. Subscribe and you'll get extra discounts, free gifts, and guaranteed monthly supply. That's B-I-O-P-T-I-M-I-Z-E-R-S.com/hyman and use the code HYMAN today.

• 47:26Dr. Mark Hyman?

  There'll be like tools and devices and things that we can have to put our biology online in real time and see what's going on. And it's kind of combined with this idea of an everywhere scanner is really very futuristic. So talk about this idea of the everywhere scanner and how it's going to change how we think about our health and medicine.

• 47:44Speaker 01

  I really think of it almost like building ourselves a new augmented artificial sensory system, right? We have multiple senses. In fact, you know what? It's not sci fi at all. We already have continuous sensing.

• 48:00Dr. Mark Hyman?

  Yeah.

• 48:01Speaker 01

  We've got our entire nervous system.

• 48:03Dr. Mark Hyman?

  Yeah.

• 48:04Speaker 01

  We can sense temperature and pressure and pain and all of these things. And these sensors are woven throughout our body.

• 48:14Dr. Mark Hyman?

  Yeah.

• 48:14Speaker 01

  The only problem is they're really not great at giving us early warning of internal things that are going wrong. They're really good at telling us, don't touch that hot stove now.

• 48:25Dr. Mark Hyman?

  Yeah.

• 48:27Speaker 01

  But they're not giving us advanced warning of cancer. That's not what they evolved to do. I think what we're talking about with everywhere scanner and with abundant sensors is basically building that artificial nervous system that's giving us early warning of all kinds of other biological things that we just didn't happen to develop nerves for.

• 48:48Dr. Mark Hyman?

  Yeah.

• 48:49Speaker 01

  And, you know, I think the body, quite frankly, it's a remarkable piece of engineering. I think we should pay attention to what it's built. Certainly in imaging, almost every innovation in vision that has, you know, that has evolved has been copied and improved upon with an artificial imaging device somewhere. Every single thing that the eye does, we can learn from and that the brain does in processing vision. Likewise, I think when we think about this network of continuous sensing. We should look at what the body's built and build on that.

• 49:26Dr. Mark Hyman?

  It's kind of cool. I mean, I rented a car recently and the thing just senses everything. It's like I drive under a bridge and the Google Maps turns a different shade. Or I'm driving down the road and there's no car in front of me, it turns the brights on. And when a car is coming, it turns the brights off. Or when like, you know, every little like, I literally took my hands off the stool and I said, hey, put your hand on someone. It looked in my eyes and I looked away for something. I was like, oh, make sure your eyes are on the road. I'm like, wow, this is car spying on me, but it's sensing everything all the time, all around it. And, you know, kind of like a Waymo or Tesla, which, you know, the self-driving is the same thing. And so we're talking about is augmenting the sensing of our own biology through various kinds of tools,

• 50:08Dr. Mark Hyman?

  whether they're intermittent or continuous tools that allow us to put our biology in a different context and to understand it over time and to not have this episodic, often too late to the game diagnostics, which, which unfortunately, you know, with medicine, when you find things too late, it's, it's often hard to fix, right? And, and so I think particularly around cancer, you know, my father died of cancer. My sister died of cancer. She had cancer twice. You know, I don't want to die of cancer. I go on, I want to live a long, healthy life. And I feel like it's one of those things that we now actually potentially with the gallery test and liquid fobses, the regular imaging and even the proteomics that are coming, we literally could make cancer

• 50:52Dr. Mark Hyman?

  and dying of cancer a historical fact.

• 50:55Speaker 01

  I, I believe so and I hope so.

• 50:57Dr. Mark Hyman?

  That's, that's really the, it's part of the mission of functional health is to do that. And to relieve so much suffering because there's so much suffering with cancer. And I, you know, I just, you see it all the time and it, I know it in my family. And I've seen my own relatives just wither away and die. And it just, it's such a heartbreak. And it's, it's in some ways, you know, if we had this proactive preventive approach to medicine, we wouldn't be in this situation.

• 51:19Speaker 01

  Absolutely. And, and my family has had that type of cancer history as well. And I, I just wish that we had had these tools earlier.

• 51:29Dr. Mark Hyman?

  It, it's giving us insight into human biology in a way that was never had before. And we're able to then on top of that, apply the 39 million scientific papers that have been published on PubMed to filter and understand all that information. They're, they're taking the. You know, all the sort of case studies we could apply, all the training that we've done based on root cause medicine into the system. And so when you put your data into function, you're actually putting your biology online and combined with these large language models and the advances and those we're seeing every day, we're entering an era where we're really truly be able to understand the body in a

• 52:10Dr. Mark Hyman?

  way we never have before and look at the patterns in the data and create an early, early assessment and continuous monitoring over time rather than episodic kind of random checking to really know what's going on in your body. And then to be able to sort of understand the subtle changes, the differences, to look at the patterns in data, to learn and to advance science, to help individuals with their own issues. It's really quite amazing. So I would love some of you for you to unpack your vision of what we're doing with the medical intelligence lab, where we're headed and what we want to build in the world. Because I think this is really foundationally revolutionary to medicine and science itself. And I think it's going to change everything we know about human health and biology.

• 52:53Speaker 01

  I think of it a little bit like a GPS for health. And if you unpack what a GPS does, it actually has a lot of the features that you talked about. First of all, you need a map, right? That's all of the accumulated medical knowledge that you're talking about. You need to know what the landscape is like that you're navigating through, otherwise you're going blind. But more than that, you also need to know your personal history. That's your biology that you've put online, right? Because if you don't know where you've come from, you know, you don't know what road you're on, I mean, you kind of need to know that individualized information, not just the collective information. And then the key thing, which I think we're really working hard on in the medical intelligence

• 53:37Speaker 01

  lab is how do we create that guideline? That gets you where you want to go, that travels with you. And make sure you get to a hundred healthy years. And that involves then taking all of these patterns that we've learned, the population-wide patterns and the individual patterns based on your data and projecting them forward and making predictions. Hey, listen, if you just keep on steering this way, you're headed for trouble. No, maybe you need to do a little course correction, change your diet, change your exercise, you know, go in for another test at this interval, that type of thing.

• 54:17Speaker 01

  And I think it is definitely a remarkable time when we can think about creating that sort of comprehensive GPS. You mentioned that big tech is already, you know, gunning for this space. It's happening regardless of whether, you know, we in medicine are comfortable with it or not. I sort of see it as both our responsibility and our privilege to try to bring the science of medicine to that endeavor, rather than just feeding lots and lots of data to chatbots.

• 54:54Speaker 01

  Really trying to bring the collection of medical knowledge and the knowledge about integration of body systems.

• 55:05Dr. Mark Hyman?

  And the context as you're talking.

• 55:06Speaker 01

  And the context and your individual context.

• 55:09Dr. Mark Hyman?

  Yeah, that's what I mean, yeah.

• 55:10Speaker 01

  Exactly. To this problem so that we're not just generating a nice sounding set of answers to questions. We're actually providing you with a guide. We're giving you that map to your help.

• 55:22Dr. Mark Hyman?

  And it's those little course corrections that make the difference, right? If you see, you know, if you track your blood sugar and you go, well, you know, it was seventies fasting, well, then it's eighties next year, or maybe the next year is to go like to eighty five and then maybe the next year is eighty nine and then, oh, you're, oh, I'm getting worse metabolic disease and I'm going to, I'm heading towards prediabetes and type diabetes, even if I don't have the official diagnosis yet, and I can course correct.

• 55:47Speaker 01

  And in fact, going back to this model of biological senses, you had talked about the concern that some people legitimately have, well, I don't want to be anxious all the time. I don't want to be thinking about the diseases I might develop. If you think about our senses. They evolved to protect us from harm in a similar way. We don't think about them all the time. We just get this burst of alarm if we step into a street and we see there's a car coming.

• 56:11Dr. Mark Hyman?

  Yeah.

• 56:12Speaker 01

  But most of the time, the sensors are just operating in the background, keeping us alive.

• 56:15Dr. Mark Hyman?

  Right.

• 56:16Speaker 01

  That's how I see this online biology and this network of sensors in the future. It's not constant alarm. It's just waking up and giving you a ping if you're about to step into the street with a car coming. Medically.

• 56:32Dr. Mark Hyman?

  Yeah.

• 56:33Speaker 01

  That type of safety net is something that even the most kind of squeamish people might be comfortable with. It's just, you know, for the moment, don't do this because it's going to harm you. But otherwise, live your life and live your life well.

• 56:47Dr. Mark Hyman?

  That's right. And I think, I think we know so much now about how to prevent disease. And I think people are worried about finding out something that they can't do anything about. And I understand that. But most of the time, you know, your biology is changeable. And there are early detection signs that are, as I mentioned, these biochemical changes. And these then turn into pathological only change we can see on scanning. That, that really give us a roadmap to what's happening with our health. And it, it, it, putting our head in the sand and not paying attention and not looking at our own personal data. It doesn't make any sense. Now you go, well, I'm not a doctor. How do I make sense of it all? And you know, yeah, you're right. It's if you don't know how to sort of make sense of it all, then it's a lot.

• 57:29Dr. Mark Hyman?

  But if you have the facilitation of a company like Function Health that provides you with a guidance, provides you with the intelligence behind it to make sense of it, to create a ranked order priority list of what you have to address, to help you understand what the steps are. You can take yourself when you need, you know, to do self-care and when you need to see, seek medical care and provide that whole continuum of care for you, rather than just sort of waiting around until something's happening. That's the thing that most people don't realize is that disease doesn't just happen. It's occurring because of low-grade changes over many decades. And the thing I want to sort of, sort of end with here is our bodies are this highly intelligent system that want to be healthy. Your body is not designed to be sick.

• 58:14Dr. Mark Hyman?

  It's not a design flaw. We are providing the conditions in our current modern society for the body to be sick with the crap food that we're having available. Seventy-three percent of the food on grocery store shelves is not even technically food. It's ultra-processed Frankenfoods. And we have enormous amount of environmental exposures and toxins that sometimes we can do things about and actually help our bodies detoxify. We have dysregulated circadian rhythms and sleep. We have excess chronic stress. We have all these things, sedentary lifestyles. These are things that we are empowered to do something about. We have nutrient deficiencies which you can do something about. And when you actually can know what's happening early,

• 58:55Dr. Mark Hyman?

  then you can make changes that really change that course and allow your body to provide the conditions that are going to create health, rather than simply waiting until you have to really treat some serious disease. And this is a fundamental paradigm shift, is the idea that disease isn't just some random phenomenon. It's something you can predict from early indicators and then do something about. And I just saw a patient yesterday with Parkinson's disease. He'd been, you know, had warning signs way early. He had tremendous amounts of environmental exposures from hobbies and being in the Navy as a chemical engineer and in childhood. And I'm like, this guy's, you know, would be a sitting

• 59:36Dr. Mark Hyman?

  duck for some type of toxin-related illness. And Parkinson's is a well-known toxin-related condition. And yet, he had to wait until he got Parkinson's for someone like me to look at his history and go, well, gee, you know, we gotta, we gotta get all this crap out of your system and we've got to detoxify you. And that was something that he didn't have to necessarily do. If he'd been proactive and actually was able to measure the toxic load of his body early on. And for same thing happened to me. I had heavy metal poisoning from, you know, but I wasn't, I wasn't sick right away. It was like this kind of slowly building up burden of toxins that then knocked me off my feet. But if I'd have known early, I could have done something about it. Would not end up in this catastrophic illness. So

• 1:00:19Dr. Mark Hyman?

  I think we can actually see these changes over time. We can do something about them if we have the right information. And he just didn't have the right information. So that's really why I think medical intelligence is such an important concept. And in our medical intelligence lab at Function Health and the science we're putting behind it and the effort we're putting behind, really providing the best quality, understanding information of your biology is going to change medicine and healthcare.

• 1:00:42Speaker 01

  Here, here. No, and, and listen, Mark, I mean, we started the conversation with the future of seeing, right? In some ways, I think in a nutshell, the future of seeing involves actually looking.

• 1:00:53Dr. Mark Hyman?

  Yeah.

• 1:00:53Speaker 01

  Now that we have the capability, now that we have the capability to see lots of your biology, now that we have the capability to use AI and other similar tools to integrate that, to connect it to knowledge that has been accumulated over all of these centuries. Now is the time when we, we need to start living with our eyes open and living with that kind of guidance.

• 1:01:18Dr. Mark Hyman?

  So the future of seeing, your book, which everybody should get a copy, where can they find it?

• 1:01:22Speaker 01

  They can find it at Columbia University Press or on Amazon, of course.

• 1:01:26Dr. Mark Hyman?

  Columbia University Press.

• 1:01:29Dr. Mark Hyman?

  Of course. It's a great title, The Future of Seeing, because it's not literally just about imaging. And your book is about imaging, but it's also, you know, implies that the future of seeing is about the future of seeing deep into human biology in a way we've never been able to do historically. And it will transform medicine, healthcare from the outside in. Because traditional healthcare is not changing anytime fast. The edifice is too solid and the resistance is too much and the old ideas die very hard. I mean, I think, you know, there's a book I read in college called The Structure of Scientific Revolutions by Thomas Kuhn.

• 1:02:03Speaker 01

  Yes.

• 1:02:03Dr. Mark Hyman?

  And in this book, he talked about this idea of a paradigm shift. And he, that's where the word paradigm shift came from. And, and in the book, he talks about this idea of normal science. What we believe is just so embedded that we can't unsee it. In other words, if you were living in, you know, 1400, the earth was flat. If you were living in the pre-Galilean era, the earth was the center of the universe, right? This is something now that, that we, we, we have to understand because we are, we are living in a totally different era where we can actually see things that we never could see before. We can look where we never looked before. I mean, look.

• 1:02:47Dr. Mark Hyman?

  I remember, I mean, let's see, it was 13 years after I graduated from medical school that we decoded the human genome. So, I mean, this is in a very short time, and that was a billion dollars. Now it's $200 to decode your own personal genome. That's where we're going. We're going to this massive, personal, data-driven healthcare system. And I think in a way, we're disrupting healthcare because we're going to empower people to be, in a way, their own healthcare agent. And then, yes, use medicine and use hospitals and use surgery and use doctors when you need them. But most of the things that we pick up early, they're fundamentally things that are under our control. It's what

• 1:03:32Dr. Mark Hyman?

  we eat, it's how we move, it's how we sleep, it's how we manage stress, it's our relationships, it's our toxin exposures, which can mitigate to some degree. Those are all the things that are driving disturbances in our health. And those are things that we can pick up in these early warning signs, like your car, okay, your tire pressure's a little low, or your engine light's a little thing, or whatever, like, I don't know, these sensors are amazing on these cars. And it wouldn't it be great to have that dashboard for your body? And that's really what we're doing with Function Health, and it's just going to get better and smarter. So I encourage everybody to, you know, not just because I co-founded the company, but I encourage everybody to think about how do you put your biology online so you can be proactive about your health and not get that horrible sinking feeling in your stomach when you're in the doctor's office, they say, you've got metastatic cancer.

• 1:04:16Dr. Mark Hyman?

  You know, Chris Vanderbeek, I think, I think is his name, was this actor who recently died of cancer. And, you know, he didn't need to, he really didn't need to, you know, my sister didn't need to, my father didn't need to. And I wish this technology was around then. And I think this is really what we're talking about here, Dan. So, any final thoughts or words for people listening?

• 1:04:37Speaker 01

  I think you said it beautifully, Mark. I think really my final words are in this remarkable era, keep your eyes open. Get that biology online. Figure out how you can essentially have this new safety net that that nobody in the history of humanity has had before.

• 1:04:57Dr. Mark Hyman?

  Yeah, amazing. Well, thank you, Dan. Thank you for your work. I'm excited to work with you in building the Medical Intelligence Lab and keep function evolving and helping it to actually help billions and millions of people. I think we're just getting started. So people should stay tuned. You can learn more about Dan's work through his book, The Future of Seeing. Go to functionhealth.com to learn more. It's only a dollar a day to join as a member and that will give you a deep dive on your biology and you can get a full body MRI scan as a baseline through that website and even more deeper scans if you want for other things. So I'm really excited about what we're doing together. I think combining the ability to gather your history data, your EMR, your wearables, imaging,

• 1:05:38Dr. Mark Hyman?

  lab data, all putting it together and helping people understand their biology is really revolutionary. I'm so super excited about it.

• 1:05:45Speaker 01

  Thank you so much, Mark. It's a pleasure and a privilege to talk with you and to work with you.

• 1:05:49Dr. Mark Hyman?

  Amazing. Well, thanks, Dan.

• 1:05:51Dr. Mark Hyman?

  If you love this podcast, please share it with someone else you think would also enjoy it. You can find me on all social media channels at Dr. Mark Hyman. Please reach out. I'd love to hear your comments and questions. Don't forget to rate, review, and subscribe to the Dr. Hyman Show wherever you get your podcasts. And don't forget to check out my YouTube channel at Dr. Mark Hyman for video versions of this podcast and more. Thank you so much again for tuning in. We'll see you next time on the Dr. Hyman Show. This podcast is separate from my clinical practice at the Ultra Wellness Center, my work at Cleveland Clinic, and Function Health, where I am Chief Medical Officer. This podcast represents my opinions and my guests' opinions. Neither myself nor the podcast endorses the views or statements of my guests. This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional.

• 1:06:36Dr. Mark Hyman?

  This podcast is provided with the understanding that it does not constitute medical or other professional advice or services. If you're looking for help in your journey, please seek out a qualified medical practitioner. And if you're looking for a functional medicine practitioner, visit my clinic, the Ultra Wellness Center at UltraWellnessCenter.com and request to become a patient. It's important to have someone in your corner who is a trained, licensed healthcare practitioner and can help you make changes, especially when it comes to your health. This podcast is free as part of my mission to bring practical ways of improving health to the public. So I'd like to express gratitude to sponsors that made today's podcast possible. Thanks so much again for listening.

• 1:07:14Dr. Mark Hyman?

  When it comes to supplements, you only want the best for your body, the kind with the highest quality, cleanest, and most potent ingredients you can get. That's exactly what you'll find at my supplement store, where I've hand-selected each and every product to meet the most rigorous standards for safety, purity, and effectiveness. These are the only supplements I recommend to my patients, and they're also what I use myself. Whether you want to optimize longevity or reduce your disease risk, or you're looking to improve your sleep, blood sugar, metabolism, gut health, you name it, DrHyman.com has the world's best selection of top-quality, premium supplements, all backed by science and expertly vetted by me, Dr. Mark Hyman. So check out DrHyman.com because when it comes to your health, nothing less than the very best will do. That's DrHyman.com, D-R-H-Y-M-A-N dot com.