
Hosted by Jason Calacanis
Written by a model from the transcript; not yet reviewed.
This episode covers the massive productivity gains and workflow shifts driven by new AI agent tools like Grokbot, alongside a deep-dive conversation with Oliver Cameron, CEO of Odyssey, about world models, physical AI, and the growing plausibility of simulation theory. The host and the guest discuss how AI agents with context and access to virtual machines are automating complex tasks from software development to design, achieving dramatic value multiples on modest spend. Later, they examine the societal pushback against data centers, the rise of space-based compute, and the rapid pace of automation across industries.
The hosts introduce the episode, highlight Grokbot’s popularity, and discuss user concerns about usage limits and cost.
Hosts showcase how Grokbot can automate content creation, design, and research, saving hours of manual work.
Discussion of Grokbot’s tiered pricing, how users hit limits quickly, and Elon Musk’s comment on unsustainable costs.
The team explains Paper’s AI-native legal platform that automates startup legal work, saving time and money.
The hosts bring in Odyssey CEO Oliver Cameron to discuss the viral simulated fruit‑fly video and its implications for simulation theory.
Odyssey reveals its funding, hiring status, and future expansion across the Bay Area, London, and Zurich.
Discussion on the computational limits of simulating large populations and the philosophical implications of being in a simulation.
Oliver explains how Odyssey trains world models on visual data to enable robots and agents to learn general physics and tasks.
Jason explains how he uses GoDaddy for domain registration and quick redirects.
Discussion of American opposition to data centers and potential rebranding as AI compute campuses.
Exploration of how AI will reshape employment, political views, and the need for inclusive policies.
Debate over how data center companies should contribute to local communities, taxes, and infrastructure.
Automating Multi-Step Tasks with AIstrategy
The host explains how instead of using basic chatbots, they now use specialized AI bots to register domain names, publish to the web, and source design references.
Measuring AI Output Value Multiplesdata
The hosts calculate that spending $40,000 a year on AI tools yields over $2 million in value by automating multiple full-time roles.
Simulating a Fruit Fly Brainstory
Odyssey's viral project placed a mapped fruit fly brain inside a real-time AI-generated world model to observe its navigation behavior.
Training Foundation World Modelsinsight
Cameron explains that Odyssey trains world models on vast visual data to learn physics, gravity, and cause and effect for physical AI agents.
90% Sure We Live in a Simulationinsight
Odyssey CEO Oliver Cameron states he is 90% certain that reality is a very advanced simulation, pointing to recent real-time generative world models.
Google's First Space Data Centerstory
Google successfully tested running AI models on TPU chips aboard a prototype satellite launched into low Earth orbit.
Data Center Public Opinion Oppositiondata
Data shows 66% of Americans oppose new data centers being built in the U.S., with opposition hitting 80% among people aged 30 and under.
“We would need five or six developers and two full-time designers and two project managers.”
“If you haven't used the last 90 days worth of products for at least 30 hours a week, you have no idea how profound the software is.”
“I think we're getting about $2 million in value and 40,000 in spend. So now you kind of do some math there.”
“We build world models and we believe that world models are a true foundation model.”
“Data centers probably take out like 0.00001% of Earth.”
“They asked Gemma four, that's the model running on board to write a haiku about being in space.”
“I don't even think there's any stopping. You can become irrelevant or you can let people's agents in.”
This Week In Startups is made possible by: Paper: https://getpaper.ai/twist G2i: https://G2i.co/twist Northwest Registered Agent: https://www.northwestregisteredagent.com/twistdomain Plaud: https://Plaud.ai/twist Today’s show: Odyssey co-founder and CEO Oliver Cameron builds simulated worlds for a living, so we asked him the obvious question: are we all living in one, right now? He says he’s 90% certain that, yes, we are. To help make the case (and show off their world model technology), Oliver’s team dropped a simulated fruit fly brain into an AI world, that’s being rendered and created in real time. So far, on X, 6.2 million people have watched the virtual fly navigate an imaginary world. On TWiST, we’re digging into how world models learn about physics, gravity, and causality just by watching videos, what make Odyssey-3 an ideal trainig ground for AI agents, and why a world model only renders the parts of the world that are currently being experienced. It’s a peek inside the technology that may, one day, allow us to enslave people in The Matrix and turn them into batteries. Or train self-driving cars more effectively! One of those. Plus: SpaceX throttles Grok Bot over unsustainably high costs, but Jason says it’s worth every penny. And will OpenAI’s suggested name change from data centers to “compute campuses,” and Meta’s efforts to improve El Paso, help turn around American attitudes? Or is blasting them into space the only remaining viable option? Guest Oliver Cameron on X: https://x.com/olivercameron Odyssey: https://odyssey.systems/ Relevant Links The fruit fly brain flying inside Odyssey-3 (6.2M views): https://x.com/odysseyml/status/2111589148146749616 Meet Odyssey-3, Odyssey's foundation world model: https://odyssey.systems/meet-odyssey-3 FlyWire: https://flywire.ai/ Nick Bostrom, "Are You Living in a Computer Simulation?”: https://simulation-argument.com/simulation.pdf Do we live in a simulation? Chances are about 50-50 (Scientific American): https://www.scientificamerican.com/article/do-we-live-in-a-simulation-chances-are-about-50-50/ "Beyond Perception: Proposing Our Reality as an ASI Alignment Simulation" (Ali Eslami, IPI Letters): https://ipipublishing.org/index.php/ipil/article/view/350 The double-slit experiment explained (Royal Institution, Jim Al-Khalili): https://www.youtube.com/watch?v=A9tKncAdlHQ “A Glitch in the Matrix” trailer: https://www.youtube.com/watch?v=au8eT79WUJ0 Elon Musk throttles Grok Bot limits over "unsustainably high" costs (TechCrunch): https://techcrunch.com/2026/11/02/elon-musk-throttles-grok-bot-limits-due-to-unsustainably-high-costs/ Elon's post: "The cost of serving Grok Bot was unsustainably high relative to revenue”: https://x.com/elonmusk/status/2116992258520064397 Jason's post: "< $40k a year on tokens… getting $2m+ in value": https://x.com/Jason/status/2117126320962351277 Grok Bot: https://x.ai/bot Plaud Web: https://web.plaud.ai Founder University Japan: https://japan.founder.university/ Most Americans say AI is bad for society and oppose more data centers (ABC/WaPo/Ipsos): https://abc7ny.com/story/most-americans-say-ai-is-bad-society-oppose-more-data-centers-abcpostipsos-poll/19964027/ Chris Lehane's memo: AI will be the issue in 2028 (TNW): https://thenextweb.com/news/chris-lehane-memo-openai-2028-ai-election Meta touts El Paso water and grid pledges as council weighs incentives (KFOX): https://kfoxtv.com/news/local/meta-touts-10b-el-paso-data-center-water-and-grid-pledges-as-council-weighs-incentives UT Austin's Texas Advance Commitment (free tuition under $100K): https://admissions.utexas.edu/cost-aid/financial-aid/texas-advance-commitment/ Andrej Karpathy's HackerTube post: https://x.com/karpathy/status/2116957135661945283 Jason's "Unsponsored" Chrome extension for Amazon: https://x.com/Jason/status/2116380861167714594 Google's first data center satellite is online and writing poetry (TechCrunch): https://techcrunch.com/2026/10/30/googles-first-data-center-satellite-is-online-and-writing-poetry/ What is low Earth orbit? (Universe Today): https://www.universetoday.com/articles/what-is-low-earth-orbit Timestamps: 0:00 Grok Bot users are at their limit 3:36 How Jason and LAUNCH get $2M+ in value out of AI 5:46 Jason’s Grok-made jacket lookbook 10:35 Paper is the legal backbone for thousands of startup founders and fund managers - including Jason. Use https://getpaper.ai/twist to get your cap table free for a year - or two years if you're leaving Carta. 14:12 Everything changed in AI over the last 90 days 20:41 G2i has been recruiting software engineers for over a decade. Go to https://g2i.co/twist to find out how G2i vets engineers, and can help you hire them in days, not weeks. 22:06 Plaud: If your work depends on conversations - interviews, meetings, calls - you need a Plaud NotePin S. You can check it out at https://plaud.ai/twist and use code TWIST for 10% off! 22:37 Wiring our Plaud into our Grok Bot 23:24 Odyssey’s fruit fly video zooms to 6.2M views 27:32 All About Simulation Theory 34:34 Got a new business idea? Northwest Registered Agent helps you bring it to life. Get a free domain, email, phone number, and more - with no purchase required! Learn more at https://www.northwestregisteredagent.com/twistdomain 38:33 What is the double slit experiment? 40:47 How to teach a robot about physics 50:01 OpenAI’s plan to make Americans love data centers 56:53 Meta’s El Paso data center pitch 1:02:26 AI companies should overfund local schools 1:06:27 Karpathy’s HackerTube project 1:13:02 Google’s first space data center goes online 1:17:51 How much room is there in low Earth orbit? Subscribe to our newsletters on Substack: TWiST: https://twistartups.substack.com/ TWiAI: https://www.thisweekinai.ai/ TWiVC: https://thisweekinvc.substack.com/ Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Thank you to our partners: Paper is the legal backbone for thousands of startup founders and fund managers - including Jason. Use https://getpaper.ai/twist to get your cap table free for a year - or two years if you're leaving Carta. G2i has been recruiting software engineers for over a decade. Go to G2i.co/twist to find out how G2i vets engineers, and can help you hire them in days, not weeks. Got a new business idea? Northwest Registered Agent helps you bring it to life. Get a free domain, email, phone number, and more - with no purchase required! Learn more at https://www.northwestregisteredagent.com/twistdomain Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin S. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com
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