
All-In with Chamath, Jason, Sacks & Friedberg
Hosted by David Friedberg
Written by a model from the transcript; not yet reviewed.
David Friedberg interviews Michael Kratsios, the Director of the Office of Science and Technology Policy, about the administration's science agenda, federal research funding, and the perceived anti-science stance of the government. They discuss the inefficiencies in federal science funding, the allocation of billions of dollars to DEI-related initiatives and extreme climate modeling scenarios, and the need to return to the core principles of the scientific method. Kratsios explains the new "Science: A New Golden Age" report, which proposes meta-science experiments, golden tickets for reviewers, flexible grant durations, and large-scale initiatives like the Genesis Mission to double U.S. scientific output using artificial intelligence. The conversation also covers the competitive race with China, the decline of homegrown STEM graduates, and the fallout from the COVID-19 pandemic on public trust in science.
Throughout the interview, the guest and host argue that the traditional model of pumping money into academic institutions without evaluating outcomes has led to a steep decline in return on investment, famously known as Arum's Law. They explain that federal funding must shift toward early-stage, pre-competitive basic research and empower individual scientists rather than bureaucratic university boards. Additionally, they address the challenges of retaining foreign STEM talent, reforming immigration pathways, and avoiding the centralized, bureaucratic traps that hamper innovation in other countries like China.
Listeners will find this episode worth hearing because it offers a rare, behind-the-scenes look at White House science policy and concrete proposals for reforming billions in federal research spending. The discussion tackles controversial topics directly, from COVID-19 era policies and climate change models to the geopolitical technology race with China, providing actionable insights into how the government plans to restructure scientific funding over the coming years.
The hosts set the stage, introducing the topic of science policy and the guest, Michael Kratsios, and outline the episode’s focus on Trump’s science agenda and current science funding debates.
Kratsios explains the Office of Science and Technology Policy’s purpose, its coordination across agencies, and his previous role as the U.S. Chief Technology Officer.
Kratsios discusses how a significant portion of NSF funding has been directed toward DEI initiatives, arguing this politicization diverts resources from pure research and highlighting cuts to climate science funding.
Kratsios counters claims that the administration is anti‑science, citing the 2024 report “Science: A New Golden Age” and arguing that science has been politicized and needs a return to fundamentals.
Discussion on pediatric societies' stance on masking and protests.
Exploration of how COVID eroded public trust in science.
Highlighting the median age of NIH researchers and its impact.
Discussion of NIH statistics and opportunities for young researchers.
Explanation of the R&D priorities memo and its implications.
Hope that science initiatives will gain bipartisan support.
Speculation on how future administrations might affect science policy.
Final thanks and wrap‑up of the episode.
Coordinating U.S. Science and Technologyinsight
The guest explains that the Office of Science and Technology Policy coordinates efforts across disparate agencies like the National Science Foundation, Department of Energy, and DARPA to set the national agenda.
The guest highlights that an analysis by Senator Ted Cruz found roughly one quarter of National Science Foundation grants during the Biden administration went toward DEI-related initiatives.
Pulling Down Extreme Climate Scenariosinsight
The guest explains that climate scientists recently removed the extreme RCP 8.5 scenario from IPCC predictions because it could not be substantiated with scientific integrity.
Arums Law in Federal Fundingdata
The host notes that despite NIH funding more than tripling since 1998, breakthrough treatments have not risen proportionally, reflecting a sharp drop in return on investment.
Golden Tickets for Grant Reviewersstrategy
The guest describes an experiment at the National Science Foundation where reviewers are given golden tickets to unilaterally approve bold research ideas outside committee consensus.
Portable Early Career Fellowshipsstrategy
The guest highlights the Graduate Research Fellowship Program, which awards portable funding to aspiring PhDs so they can choose their university and focus on research.
The Genesis Mission Initiativestrategy
The guest outlines the administration's flagship Genesis Mission, which aims to double U.S. scientific output by applying artificial intelligence to hard scientific challenges.
“I think one of the things that I'm most proud of is the release of a new report a couple of weeks ago called "Science: A New Golden Age."”
“And if you think about that, that's an astronomical amount. That is roughly $2 billion a year times four years. That's $8 billion of science funding that went to these DEI-related initiatives.”
“We want to empower our young scientists. We want to create an ecosystem that allows our greatest scientists to work on the hardest problems everywhere in the U.S.”
“We have to win on things like on AI, on quantum, on nuclear, on bio.”
“the median age of an intramural researcher at NIH is 71 years old.”
“you can agree with some things, disagree with other things. But if you don't agree with it all, you're anti-science.”
“we have to allow people to understand and trust what science is about and see that it's inspiring and a good thing and can change our way of life.”
“the top five research agencies, those with over $3 billion in, in R and D, have a report due back to us 90 days after the publication on how they're going to be doing implementation.”
“I think those are things that, that you mentioned. And I think that memo kind of serves as the policy in United States on how agencies like NSF should be prioritizing those things.”
(0:00) Michael Kratsios joins the show! (01:56) Is this administration anti-science? The Nature poll, DEI grants, and $8B down the drain (8:16) Climate science cuts: RCP 8.5 gets pulled and the "climate emergency" narrative collapses (13:45) $47B at NIH, Eroom's Law, and golden tickets: has American science stagnated? (22:24) Big bold bets: Genesis Mission, quantum by 2028, fusion by 2035, boots on the moon in '28 (34:04) The great race with China: $33B to $670B, and 7 out of 10 STEM PhDs aren't American (44:09) Fauci did more damage to science than anyone in modern history, and NIH's median researcher is 71 Follow the besties: https://x.com/chamath https://x.com/Jason https://x.com/DavidSacks https://x.com/friedberg Follow on X: https://x.com/theallinpod Follow on Instagram: https://www.instagram.com/theallinpod Follow on TikTok: https://www.tiktok.com/@allin Follow on LinkedIn: https://www.linkedin.com/company/allinpod Intro Music Credit: https://rb.gy/tppkzl https://x.com/yung_spielburg Intro Video Credit: https://x.com/TheZachEffect #allin #tech #news
10,973 words · 2 speakers
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