
Hosted by John Coogan and Jordi Hays
Written by a model from the transcript; not yet reviewed.
This episode covers a massive week in tech, featuring breaking cybersecurity alerts, new product launches, and strategic business developments. Cloudflare CEO Matthew Prince joins the show to break down a critical remote code execution vulnerability in PHP affecting 70% of the web, explaining how AI models like OpenAI's are helping defenders find hidden software vulnerabilities before bad actors exploit them. Later segments feature interviews with startup founders building next-generation infrastructure, including Warp Sciences scaling robotic labs for domestic drug discovery, Stellius developing high-power microwaves for drone defense, Plant Switch replacing single-use plastics with biodegradable plant-based materials, and Pulsar Space Systems building modernized satellite navigation services to combat GPS jamming. The hosts also discuss Meta introducing new Class C stock to help Mark Zuckerberg manage voting control and tax strategy, alongside early reactions to the iPhone Duo.
Hosts introduce the show, guests, and set the stage for the discussion.
Matthew Prince explains how the PHP vulnerability was discovered, disclosed, and patched over the past two months.
Matthew Prince details Cloudflare’s rapid response mechanisms and use of AI to defend against threats.
Discussion on whether everyday users need to take action or if the issue is limited to web servers.
Exploration of how AI is used by both attackers and defenders, and how attack patterns are changing.
Discussion of Meta’s new Class C stock issuance and its impact on tax strategy for executives.
Host introduces Kevin Williams and Warp Sciences, explaining their mission to accelerate drug discovery with robotic labs.
Warp explains how robotics and AI will speed science, reshore capabilities from China, and build a next‑generation contract research organization in the U.S.
Dylan Baxter discusses Plant Switch’s zero‑waste, plant‑based materials, vertical manufacturing, and expansion into coffee cup liners to eliminate microplastics.
Kevin details Warp’s $215 M raise, team composition, and decision to build vertically integrated capabilities rather than acquire existing CROs.
The new Cognition Industries initiative is explained, focusing on industry‑specific AI teams, partnership models, and the plan to tackle the 14 largest sectors.
Richard Starson outlines Stellius’ mission to build U.S.‑made high‑power microwave systems for drone defense, counter‑electronics, and future fusion research.
Brian Manning explains Uzona’s first‑in‑class satellite navigation service, launch strategy, and scaling manufacturing to meet growing satellite counts.
The hosts discuss how satellite companies are adopting automotive engineering practices to build efficient, cost-effective constellations.
Uncovering the Major PHP Vulnerabilitystory
OpenAI and security researchers discovered a critical remote code execution vulnerability in PHP affecting nearly 70% of the web. Cloudflare implemented a free background protection for all customers while the PHP Foundation prepared a patch.
AI as the Defenderinsight
Cloudflare CEO Matthew Prince explains that AI is not the bad guy in recent cybersecurity breaches; rather, frontier AI tools have infinite patience to find hidden vulnerabilities in legacy code so defenders can fix them.
The Future Business Model of the Internetinsight
Matthew Prince predicts that agentic traffic will outpace human internet traffic by a thousand times in five years, requiring a transition to micropayments and agent-targeted advertising to solve the tragedy of the commons.
Reshoring Pharmaceutical Infrastructurestrategy
Warp Sciences' founder explains that outsourcing low-skilled drug discovery work to China eventually leads to an atrophy of domestic manufacturing and innovation capabilities, mirroring the decline of American solar and manufacturing sectors.
Building Robotic Labs in Americadata
Warp Sciences raised $215 million led by Lightspeed to build automated robotic laboratories in the United States, accelerating drug discovery and reshoring pharmaceutical manufacturing capabilities from China.
Replacing Single-Use Plasticsstory
Plant Switch developed a fully vertically integrated production process to create biodegradable plant-based straws and cutlery, and is expanding into paper coatings and coffee cup liners to eliminate microplastics.
High-Power Microwaves for Defensestrategy
Stellius is building megawatt-class high-power microwave systems in America to provide area denial and counter-electronics capabilities against cheap drone swarms.
Next-Generation Satellite Navigationdata
Pulsar Space Systems announced a $250 million funding round at a $2.45 billion valuation, launching the first commercial satellite navigation service designed to modernize GPS and resist jamming.
“you can send some basic just requests to a server and then essentially take that server over, be able to run your own code on that server.”
“if you're running a server right now, get it updated with the latest version of PHP. It's free. It should only take a few minutes to do it.”
“AI is not the bad guy here. AI is the good guy. The AI didn't create these vulnerabilities. AI found them.”
“AI is actually helping the good guys more than it's helping the bad guys.”
“We have Kevin Williams, the founder of Warp Sciences, launching Warp Sciences.”
“Robotic labs are going to accelerate science, partly because you can just run more experiments when you have labs operating 24/7.”
“We set up a fully vertically integrated production site.”
“We raised 215 million, Lightspeed led. We had folks like IVP, Mayfield, Lux, Menlo Ventures, Scribble Ventures, a bunch of amazing folks.”
“The straws and the cutlery, which are what we got started with, you know, we're starting to see those everywhere, which is a lot of fun.”
“And so a lot of things we've done here is taking lessons on how do we build satellites more like, you know, cars?”
(00:36) - Matthew Prince on PHP2Shell. Matthew Prince is the co-founder and CEO of Cloudflare, a company focused on internet security and infrastructure. Prince discusses major cybersecurity vulnerabilities, AI’s growing role in finding and defending against threats, and why rapid software updates and industry coordination are essential. He also predicts that surging AI-agent traffic will reshape the internet’s business model through mechanisms such as micropayments. (29:12) - 𝕏 Timeline Reactions (38:05) - Meta Unveils New Class C Stock (47:07) - Kevin Weil, founder of Warp Sciences, discusses building AI-powered robotic laboratories to accelerate drug discovery and reshore critical pharmaceutical research from China to the United States. He explains the company’s vertically integrated approach, growing market opportunity, and $215 million funding round to build a next-generation preclinical contract research organization. (01:01:39) - Mc Lader discusses his role as the new head of Cognition Industries, drawing on his experience as a frontier-tech founder and former president of a stablecoin company acquired by Coinbase. He outlines Cognition’s strategy to build small, founder-led teams across 14 major industries, combining vertical expertise with Devin’s AI agents to help enterprises modernize software, strengthen security, and create industry-specific products. (01:12:16) - Dillon Baxter discusses PlantSwitch, the sustainable packaging company he co-founded to replace disposable plastics with plant-based materials that biodegrade without leaving microplastics. He explains the company’s vertically integrated manufacturing, rapid growth, major distribution partnerships, and plans to use its Series B funding to expand into plastic-free coffee cups and lids. (01:20:18) - Richard Starson, founder and CEO of Stelius, discusses building U. S.-made high-power microwave systems for defense applications, particularly neutralizing drone swarms and protecting critical infrastructure. He also outlines the company’s early funding and long-term goal of advancing compact fusion for energy, hypersonics, and spaceflight. (01:28:42) - Brian Manning, founder and CEO of space-based navigation company Xona Space Systems, discusses launching six satellites, raising $250 million, and scaling manufacturing for its commercial GPS alternative. He explains how Xona’s stronger, jam-resistant signals can improve positioning accuracy, indoor coverage, device integration, and battery efficiency for commercial and military users. (01:42:54) - iPhone Duo Early Reactions TBPN is made possible by: Ramp - https://ramp.com Public - https://public.com Cisco - https://www.cisco.com Console - https://www.console.com CrowdStrike - https://www.crowdstrike.com Figma - https://www.figma.com MongoDB - https://www.mongodb.com NYSE - https://www.nyse.com Railway - https://railway.com Shopify - https://www.shopify.com Codex - http://openAI.com/codex Follow TBPN: https://TBPN.com https://x.com/tbpn https://open.spotify.com/show/2L6WMqY3GUPCGBD0dX6p00?si=674252d53acf4231 https://podcasts.apple.com/us/podcast/tbpn/id1772360235 https://www.youtube.com/@TBPNLive
22,417 words · 7 speakers
Speaker names marked are inferred from speaking time and the show’s known hosts — they are not voice-verified.
Page updated · transcript and summary are machine-generated